Communicable Disease Control & Immunization - Cheat Sheet
Your last-minute rapid-fire revision companion for Community Health Nursing's most heavily tested chapter. Covers EPI schedules, cold chain, DOTS, dengue, notifiable diseases, and immunity concepts — all organized for 30-minute pre-exam review.
Immunity Concepts & Types
Common values
Value
~95%
Symbol
HIT
Quantity
Herd immunity threshold (measles)
Value
~80–85%
Symbol
HIT
Quantity
Herd immunity threshold (poliomyelitis)
Value
6–12 months (especially measles)
Symbol
Nat. passive
Quantity
Duration of maternal antibody protection
Important facts
- Active immunity takes TIME to develop (lag phase) but is durable; passive immunity is IMMEDIATE but FADES.
- Vaccination harnesses active immunity; it does NOT provide instant protection.
- Herd immunity thresholds vary by disease (measles ~95%, polio ~80–85%, diphtheria ~85%).
- Maternal antibodies protect newborns initially but decline by 6–12 months (why EPI starts at birth/6 weeks).
- Live vaccines (BCG, OPV, measles, MMR) cannot be given to severely immunocompromised persons.
- Immunological memory: after initial exposure (natural or vaccine), subsequent encounters trigger faster, stronger response.
Key definitions
Active Immunity
Example
Child gets measles vaccine → body makes anti-measles antibodies → protected for life.
Body produces its own antibodies; long-lasting (years/lifetime); develops from disease infection or vaccination.
Passive Immunity
Example
Newborn receives maternal antibodies via breast milk → protected for 6 months but no active immunity.
Antibodies received from external source; immediate but temporary (weeks/months); does NOT require immune response.
Herd Immunity
Example
If 85% of community is vaccinated against measles, the 15% unvaccinated are indirectly protected.
When ≥70–90% of population is immune, disease transmission stops even in unimmunized individuals (the critical threshold depends on disease).
Natural Active Immunity
Example
Person recovers from chickenpox infection → lifelong immunity to varicella.
Immunity acquired by surviving a communicable disease; strongest & longest-lasting.
Artificial Active Immunity
Example
BCG vaccination → body mounts immune response → TB protection.
Immunity from vaccination with live, attenuated, inactivated, or toxoid vaccines.
Natural Passive Immunity
Example
Newborn protected from measles for ~6–9 months from maternal IgG (wanes as maternal Abs degrade).
Maternal antibodies (IgG) cross placenta during pregnancy or IgA in breast milk.
Artificial Passive Immunity
Example
Unimmunized person exposed to tetanus → given TIG (tetanus immunoglobulin) for immediate temporary protection.
Administration of immunoglobulins or antiserum (e.g., tetanus immunoglobulin, rabies immunoglobulin).
Diagrams to know
- The 'Immunity Spectrum' — active vs passive on one axis, natural vs artificial on the other (2×2 grid).
- Timeline of antibody levels in passively immunized vs actively immunized infant.
- Herd immunity threshold curve showing % immune vs disease transmission rate.
Expanded Program on Immunization (EPI) – Legal Foundation & Targets
Common values
Value
1976
Symbol
—
Quantity
EPI launch year
Value
2011
Symbol
—
Quantity
RA 10152 enactment
Value
<8 years
Symbol
—
Quantity
Age cutoff for compulsory immunisation (PD 996)
Value
Within 24 hours of birth
Symbol
—
Quantity
Hepatitis B birth dose window
Important facts
- EPI targets: TB, diphtheria, pertussis, tetanus, poliomyelitis, measles (the classic 6).
- Program expanded to include Hepatitis B (birth dose), Hib, PCV, and MMR.
- Presidential Decree 996: compulsory basic immunisation for children <8 years.
- RA 10152 (Mandatory Infants and Children Health Immunization Act of 2011): mandates FREE routine immunisation for infants and children.
- Hepatitis B monovalent birth dose MUST be given within 24 hours of birth (RA 10152 requirement).
- FIC coverage is a KEY DOH performance indicator; low coverage signals outbreak risk.
- Vaccination must NOT be delayed for minor illnesses (low-grade fever, mild cough, mild diarrhea) — missed opportunities reduce herd immunity.
- Late vaccination is better than no vaccination; catch-up is allowed.
Key definitions
EPI (Expanded Program on Immunization)
Example
EPI provides free BCG, pentavalent, OPV, IPV, PCV, measles vaccines to all infants nationwide.
DOH program (launched 1976) to reduce morbidity/mortality from vaccine-preventable diseases in children.
Fully Immunized Child (FIC)
Example
A 10-month-old with all required doses on schedule = FIC.
Child who received 1 BCG + 3 OPV + 3 pentavalent/DPT–HepB–Hib + ≥1 measles vaccine BEFORE 12 months of age.
Completely Immunized Child (CIC)
Example
An 18-month-old who completed all EPI antigens (even if delayed) = CIC.
Same as FIC but antigens received by age 12–23 months (allows catch-up).
Child Protected at Birth (CPAB)
Example
Mother vaccinated with Td2 during pregnancy → newborn is CPAB (protected from neonatal tetanus).
Newborn protected against neonatal tetanus because mother received ≥2 doses of tetanus vaccine (Td2 or more) during pregnancy.
Diagrams to know
- EPI organizational structure (DOH → Regional → Provincial → RHU/health center).
- Timeline showing when children become FIC, CIC, and CPAB.
- Flow chart: Is the child eligible for catch-up vaccination?
EPI Routine Infant Vaccination Schedule (CRITICAL)
Common values
Value
0.05 mL
Symbol
ID
Quantity
BCG dose (infants)
Value
0.1 mL
Symbol
ID
Quantity
BCG dose (older children)
Value
0.5 mL
Symbol
IM
Quantity
Pentavalent, PCV, IPV dose
Value
0.5 mL
Symbol
IM
Quantity
Hepatitis B birth dose
Value
2–3 drops
Symbol
Oral
Quantity
OPV dose
Value
0.5 mL
Symbol
SC
Quantity
Measles/MMR dose
Value
4 weeks
Symbol
—
Quantity
Minimum interval between doses
Important facts
- SCHEDULE CORNERSTONE: 6–10–14 weeks = pentavalent, OPV, PCV (3 doses each, minimum 4-week interval).
- BCG & Hepatitis B at BIRTH (HepB within 24 hours per RA 10152).
- MCV1 (measles) at 9 MONTHS; MMR (MCV2) at 12 MONTHS (NOT before 9 months; maternal Abs interfere).
- OPV: 3 doses at 6–10–14 weeks + IPV at 14 weeks + IPV at 9 months (current combined schedule).
- Minimum interval between doses is 4 weeks for primary series (pentavalent, OPV, PCV).
- Route specificity: BCG = intradermal (0.05 mL); pentavalent/PCV/IPV = intramuscular (0.5 mL); OPV = oral (2–3 drops); measles/MMR = subcutaneous (0.5 mL).
- BCG successful take = wheal at injection site, later a small flat scar (~3–6 weeks); absence of scar may indicate vaccine failure.
- PPD/Koch's phenomenon = accelerated local reaction to BCG indicating prior TB exposure (do NOT revaccinate).
- Pentavalent = freeze-sensitive (do NOT freeze); DPT/Hep B/Td also freeze-sensitive.
- OPV = most heat-sensitive vaccine; store where coldest in cold chain.
Key definitions
Pentavalent (DPT–HepB–Hib)
Example
Given at 6, 10, 14 weeks IM in vastus lateralis (0.5 mL).
5-in-1 vaccine protecting against diphtheria, pertussis, tetanus, Hepatitis B, and Haemophilus influenzae type b.
OPV (Oral Polio Vaccine)
Example
3 doses at 6, 10, 14 weeks (same schedule as pentavalent).
Live attenuated vaccine given ORALLY (2–3 drops); protects against poliovirus types 1, 2, 3.
IPV (Inactivated Polio Vaccine)
Example
2 IPV doses: one at 14 weeks, one at 9 months (current DOH schedule).
Inactivated (killed) polio vaccine given IM; added to provide additional polio protection.
PCV (Pneumococcal Conjugate Vaccine)
Example
3 doses at 6, 10, 14 weeks IM in vastus lateralis (0.5 mL).
Protects against Streptococcus pneumoniae (meningitis, pneumonia, otitis media).
BCG (Bacillus Calmette-Guérin)
Example
1 dose at birth or anytime after, 0.05 mL ID into right upper arm/deltoid.
Live attenuated TB vaccine; intradermal injection; produces a wheal immediately, later a small scar.
Measles-Containing Vaccine (MCV1 / AMV)
Example
MCV1 at 9 months → booster MCV2 (MMR) at 12 months.
Given at 9 months; primary measles dose; subcutaneous in outer upper arm.
MMR (Measles, Mumps, Rubella)
Example
After MCV1 at 9 months, child receives MMR at 12 months for complete coverage.
MCV2 given at 12 months subcutaneously; reinforces measles immunity and adds mumps/rubella protection.
Diagrams to know
- Vaccine schedule timeline from birth to 12 months showing all 8 vaccines and their ages.
- Route comparison chart: intradermal vs IM vs oral vs subcutaneous (site, needle angle, depth).
- Freeze-sensitive vs heat-sensitive vaccine classification.
Tetanus (Td) Immunization for Women of Childbearing Age & Pregnancy
Common values
Value
ASAP during pregnancy
Symbol
—
Quantity
Td1 timing
Value
≥4 weeks
Symbol
—
Quantity
Interval Td1 to Td2
Value
≥6 months
Symbol
—
Quantity
Interval Td2 to Td3
Value
≥1 year
Symbol
—
Quantity
Interval Td3 to Td4
Value
≥1 year
Symbol
—
Quantity
Interval Td4 to Td5
Value
~3 years
Symbol
—
Quantity
Td2 protection duration (mother)
Value
~3 years (until age 3)
Symbol
CPAB
Quantity
Td2 protection duration (newborn)
Value
Lifetime
Symbol
—
Quantity
Td5 protection duration
Important facts
- Td1: given as early as possible (even first antenatal care visit); provides NO protection yet.
- Td2: given ≥4 weeks after Td1; protects newborn from neonatal tetanus (~3 years' protection to mother).
- Td3: given ≥6 months after Td2; extends maternal protection to ~5 years.
- Td4: given ≥1 year after Td3; extends maternal protection to ~10 years.
- Td5: given ≥1 year after Td4; provides LIFETIME tetanus/diphtheria protection.
- Two doses (Td1 + Td2) are the MINIMUM to protect the newborn; this is the definition of CPAB.
- Tetanus toxoid is freeze-sensitive; must be stored at +2°C to +8°C (cold chain requirement).
- Neonatal tetanus is an immediately notifiable disease (within 24 hours).
- Clean, safe delivery practices (clean hands, clean cord, clean environment) + maternal Td vaccination = elimination of neonatal tetanus.
- Traditional cord practices (use of unsterile substances) increase neonatal tetanus risk if mother is unvaccinated.
Key definitions
Td (Tetanus-Diphtheria)
Example
Pregnant woman receives Td1 during first visit, Td2 at least 4 weeks later (protects newborn from neonatal tetanus).
Combined vaccine for tetanus and diphtheria toxoids; given to women to eliminate maternal and neonatal tetanus.
Neonatal Tetanus
Example
If mother received ≥Td2, newborn is CPAB and protected from neonatal tetanus.
Tetanus in newborn (0–28 days) caused by contaminated umbilical cord; preventable by maternal Td immunisation.
Child Protected at Birth (CPAB)
Example
Mother vaccinated with Td1 and Td2 during pregnancy → newborn = CPAB.
Newborn protected from neonatal tetanus because mother received ≥2 doses of tetanus-containing vaccine (Td2 or higher).
Diagrams to know
- Td dosing schedule and protection timeline (Td1 → Td2 → Td3 → Td4 → Td5).
- Duration of protection curve: shows how long each Td dose protects (3, 5, 10, lifetime years).
Vaccine Cold Chain & Storage
Common values
Value
+2°C to +8°C
Symbol
—
Quantity
RHU refrigerator temperature
Value
−15°C to −25°C
Symbol
—
Quantity
Regional/provincial freezer temperature
Value
+2°C to +8°C (with ice packs)
Symbol
—
Quantity
Vaccine cooler temperature (outreach)
Value
2× daily (morning & evening)
Symbol
—
Quantity
Refrigerator monitoring frequency
Value
OPV
Symbol
—
Quantity
Most heat-sensitive vaccine
Important facts
- Health center/RHU refrigerator: +2°C to +8°C (standard cold room temp).
- Regional/provincial level freezers: −15°C to −25°C (for bulk OPV and measles stock).
- HEAT-SENSITIVE (most vulnerable): OPV > measles/BCG > pentavalent/DPT.
- FREEZE-SENSITIVE (must NOT be frozen): DPT, Hepatitis B, Td, pentavalent — freezing destroys potency.
- Refrigerator monitoring: thermometer checked twice daily (morning & evening); temperature log maintained.
- VVM storage rule: keep vaccines out of direct sunlight and UV light; VVM accelerates in UV.
- Shake test positive (opaque/clumpy) = vaccine frozen = potency destroyed = discard immediately.
- Vaccine coolers for outreach: use cool packs or ice; thermometer inside; ice should NOT touch vaccine vials directly (wrap in cloth).
- Expired vaccines: marked 'EXP' with thick marker, placed in 'discard box' for safe disposal.
- Cold chain breakdown (e.g., power outage, vaccine left in sun) = entire batch may be unusable — vaccine safety cannot be guaranteed.
- OPV most heat-sensitive because it's live attenuated; inactivated vaccines (IPV, Hep B) are more heat-stable but still sensitive.
- Storage order in RHU refrigerator: OPV/measles in coldest section; DPT/Hep B/Td in middle (not freezing).
Key definitions
Cold Chain
Example
Vaccine manufactured in Europe → shipped in −20°C freezer → stored in RHU at +2–8°C → transported in vaccine cooler to outreach site → administered on time.
System of uninterrupted storage, handling, and transport of vaccines within safe temperature range (manufacturer → child).
Vaccine Vial Monitor (VVM)
Example
VVM square at corner of vial: color progresses from colorless → pale → dark as heat cumulates; when color reaches (or exceeds) the circle = vaccine unsafe to use.
Heat-sensitive label on vaccine vial; changes color with cumulative heat exposure; indicates if vaccine is still potent.
Shake Test
Example
Gently shake frozen DPT vial: if liquid appears opaque/granular/clumpy = FROZEN, discard. If liquid is clear = safe.
Manual test to detect if freeze-sensitive vaccine (DPT, Hep B, Td, pentavalent) has been frozen (destroyed potency).
FEFO (First Expiry, First Out)
Example
Batch A expires 2025-06-30; Batch B expires 2025-08-15. Use Batch A first.
Stock rotation principle: use vaccines with earliest expiration dates first to prevent waste.
Diagrams to know
- Cold chain flow diagram: vaccine manufacturer → freezer → RHU refrigerator → vaccine cooler → outreach → child (with temperatures).
- VVM color progression chart showing safe → unsafe transitions.
- Refrigerator layout showing temperature zones and vaccine placement.
- Shake test visual: clear liquid = safe; opaque/clumpy = frozen/unsafe.
Contraindications & Safe Vaccination Practice
Common values
Value
<38.5°C
Symbol
—
Quantity
Fever threshold (mild = safe to vaccinate)
Value
≥38.5°C
Symbol
—
Quantity
Fever threshold (defer vaccination)
Value
Within 3 days of vaccine
Symbol
—
Quantity
Time window for severe reaction (convulsion, shock)
Value
≥3 months
Symbol
—
Quantity
Waiting period after blood transfusion (before live vaccine)
Important facts
- LIVE vaccines (BCG, OPV, measles, MMR) are contraindicated in:
- - Severely immunocompromised children (symptomatic HIV/AIDS, on immunosuppressive therapy, malignancy on chemo).
- - Do NOT give BCG to clinical AIDS; wait until CD4 recovery on ART.
- - Contraindicated during pregnancy (though accidental exposure is not an indication for termination).
- INACTIVATED vaccines (IPV, Hep B, pentavalent, PCV, Td) are safe in immunocompromised — but response may be poor.
- Do NOT defer vaccination for:
- - Mild febrile illness (low-grade fever <38.5°C).
- - Mild cough or upper respiratory infection.
- - Mild diarrhea.
- - Asymptomatic malnutrition.
- - Use of antibiotics.
- - Recent exposure to infectious disease (vaccination can still prevent).
- - Breast-feeding (live vaccines safe during lactation).
- SEVERE REACTION to prior dose (convulsions, shock, encephalopathy within 3 days) → withhold subsequent doses of same vaccine; seek specialist advice.
- Relative contraindication (defer, don't withhold):
- - Moderate-to-severe febrile illness (>38.5°C) → vaccinate when fever resolves.
- - Severe diarrhea → defer until resolved (vaccine may not be absorbed).
- - Recent blood transfusion or IG → defer measles/MMR by ≥3 months (passive Abs interfere).
- Immunization errors are NOT contraindications to further vaccination — address the error and resume schedule (catch-up).
- If unsure, vaccinate! Missed vaccination opportunities > minimal risk of adverse event.
Key definitions
True Contraindication
Example
Child with clinical AIDS/CD4 <200 → withhold BCG (live vaccine); can receive after immune reconstitution on ART.
Valid medical reason to defer or withhold vaccine (e.g., anaphylaxis to vaccine component, severe immunosuppression).
Precaution (not a contraindication)
Example
Child with mild cold and low-grade fever (37.8°C) → CAN be vaccinated; do NOT defer for minor illness.
Temporary reason to defer vaccine but NOT a permanent bar (e.g., mild febrile illness, moderate diarrhea).
Severe Allergic Reaction
Example
Child had anaphylaxis after first pentavalent dose → withhold further DPT-containing vaccines; consult pediatrician for alternatives.
Anaphylaxis (swelling of face/lips, difficulty breathing, shock) within minutes of vaccination; contraindication to that vaccine.
Diagrams to know
- Decision tree: 'Should this child be vaccinated?' (YES for minor illness; NO for severe allergy/immunosuppression).
- Common misconceptions vs. true contraindications comparison chart.
Notifiable Diseases & Disease Surveillance (PIDSR)
Common values
Value
Within 24 hours
Symbol
—
Quantity
Reporting timeframe (immediately notifiable)
Value
Weekly (aggregated)
Symbol
—
Quantity
Reporting frequency (weekly notifiable)
Important facts
- RA 9173 (Philippine Nursing Practice Law) requires nurses to report notifiable diseases as a function of community health nursing.
- Immediately notifiable diseases (24-hour reporting requirement):
- - Acute flaccid paralysis (polio surveillance).
- - Measles.
- - Neonatal tetanus.
- - Cholera.
- - Meningococcal disease.
- - Rabies (human).
- - Plague.
- - Yellow fever.
- Weekly notifiable (aggregated reporting):
- - Dengue fever.
- - Typhoid fever.
- - Dysentery (bacillary & amoebic).
- - TB (clinical diagnosis).
- Reporting pathway: frontline health worker (nurse/midwife/BHW) → RHU → City Health Office → Provincial Health Office → DOH.
- Each case triggers investigation (contacts, source, transmission) and appropriate control measures (isolation, quarantine, mass vaccination).
- Confidentiality maintained in reporting; patient identity protected per DOH guidelines.
- Failure to report is a breach of duty under RA 9173 and public health law.
- Nursing documentation must include: date of diagnosis, clinical signs, investigations, contacts, vaccination status, and isolation measures.
Key definitions
Notifiable Disease
Example
Measles case → must report within 24 hours → DOH investigates contacts → vaccination campaign if outbreak.
Disease legally required to be reported to health authorities (DOH/LGU) to trigger outbreak investigation and control.
PIDSR (Philippine Integrated Disease Surveillance and Response)
Example
Health worker identifies acute flaccid paralysis case → reports to PIDSR within 24 hours → DOH confirms/investigates polio status.
National disease surveillance system coordinating detection, investigation, and response to notifiable diseases.
Immediately/Urgently Notifiable (within 24 hours)
Example
Acute flaccid paralysis (polio), measles, neonatal tetanus, cholera, meningococcal meningitis, rabies, yellow fever, plague.
Diseases of epidemic potential and eradication targets requiring rapid response.
Weekly Notifiable
Example
Dengue, typhoid, dysentery, TB (clinical diagnosis before lab confirmation).
Routine diseases reported weekly (aggregated data) to track trends.
Diagrams to know
- Notifiable disease reporting pathway flowchart (case identification → RHU → CHO → PHO → DOH).
- Timeline of investigation and response (24 hours for urgent; 7 days for weekly).
- List of immediately notifiable vs. weekly notifiable diseases (two-column chart).
National TB Control Program (NTP) & DOTS Strategy
Common values
Value
2 months (HRZE)
Symbol
—
Quantity
Category I intensive phase duration
Value
4 months (HR)
Symbol
—
Quantity
Category I continuation phase duration
Value
6 months
Symbol
—
Quantity
Total Category I treatment duration
Value
~2 hours
Symbol
—
Quantity
Xpert MTB/RIF turnaround time
Value
End of month 2
Symbol
—
Quantity
Sputum smear monitoring (end of intensive phase)
Value
End of month 5
Symbol
—
Quantity
Sputum smear monitoring (end of treatment)
Value
Streptomycin
Symbol
S
Quantity
Most ototoxic anti-TB drug
Important facts
- Five Elements of DOTS:
- 1. Political commitment with sustained financing.
- 2. Case detection through quality-assured bacteriology (Xpert MTB/RIF or DSSM).
- 3. Standardized treatment regimen with direct observation (DOT).
- 4. Uninterrupted supply of quality-assured anti-TB drugs.
- 5. Standardized recording and reporting system.
- First-line anti-TB drugs (HRZE):
- - H = Isoniazid: hepatotoxic; monitor LFTs.
- - R = Rifampicin: turns urine/tears/sweat ORANGE-RED (normal, warn patient); hepatotoxic; monitor LFTs.
- - Z = Pyrazinamide: hyperuricemia (gout-like); hepatotoxic.
- - E = Ethambutol: optic neuritis (loss of color vision, especially red-green); monitor vision at baseline and monthly.
- - S = Streptomycin: ototoxicity (hearing loss, vertigo); nephrotoxicity; used in Category II.
- Category I regimen (most common):
- - Intensive: 2 months of HRZE daily (or 5 days/week with 2 days missed).
- - Continuation: 4 months of HR daily (or 5 days/week).
- - Total = 6 months treatment.
- - Sputum smear monitoring: end of month 2 (should convert to negative), month 5 (confirm cure).
- Direct Observation is NON-NEGOTIABLE:
- - Health worker or treatment partner WATCHES patient swallow EVERY dose (especially in intensive phase).
- - Directly observed = adherence → cure; non-observed = risk of default and drug resistance.
- Drug-Resistant TB (MDR-TB, XDR-TB):
- - Managed under Programmatic Management of Drug-Resistant TB (PMDT).
- - Requires longer regimen (18–24 months) with second-line drugs.
- - Resistance develops from incomplete/interrupted treatment.
- Contact tracing & household screening: all close contacts (especially children <5 yrs) must be screened for TB and TB infection.
- Infection control: TB patient should avoid crowded places, cover mouth when coughing, ensure ventilation at home; most infectious in first 2 weeks of treatment.
- TB notifications: presumptive TB cases (cough >3 weeks) and confirmed cases are notifiable; reported weekly.
- Treatment success definition: patient completes full regimen and is smear-negative at end of month 5.
Key definitions
DOTS (Directly Observed Therapy, Short-course)
Example
TB patient receives INH daily under health worker observation for 6 months (continuation phase after 2-month intensive phase); cure documented.
Evidence-based TB control strategy with 5 pillars: commitment, diagnosis, standardized treatment + observation, drug supply, recording/reporting.
Xpert MTB/RIF (GeneXpert)
Example
Cough >3 weeks with fever → sputum sent for Xpert MTB/RIF → rifampicin-sensitive TB confirmed → start standard Category I treatment.
WHO-recommended first-line TB diagnostic test; rapid (2 hours), detects TB and rifampicin resistance simultaneously.
Direct Sputum Smear Microscopy (DSSM)
Example
Smear-positive TB (AFB+) = infectious; must start treatment immediately and isolate during infectious period.
Sputum microscopy under Ziehl-Neelsen stain; identifies acid-fast bacilli (AFB); used for diagnosis and monitoring.
Category I (Intensive Phase + Continuation)
Example
New smear-positive TB → 2 months daily HRZE → sputum smear conversion → 4 months HR → cured.
2HRZE / 4HR — 2 months isoniazid, rifampicin, pyrazinamide, ethambutol, then 4 months isoniazid + rifampicin.
Category II (Previously Treated TB)
Example
TB relapse patient → adds streptomycin; longer duration accounts for possible drug resistance.
Longer regimen for relapse/treatment failure/lost to follow-up cases; typically 2HRZES / 1HRZE / 5HRE.
Treatment Partner
Example
TB patient's spouse becomes treatment partner; watches patient take pills daily; reports missed doses to health worker.
Reliable person (family member, BHW, DOT provider) who observes TB patient taking every dose.
Diagrams to know
- DOTS strategy 5-pillar flowchart showing feedback loops.
- TB treatment timeline: months 0–2 (intensive HRZE), months 2–6 (continuation HR), with sputum monitoring checkpoints.
- Category I vs. Category II regimen comparison.
- DSSM interpretation guide: 0 AFB, 1+ to 3+ grading.
Dengue & Vector-Borne Disease Control
Common values
Value
6 AM–10 AM & 4 PM–6 PM (day-biter)
Symbol
—
Quantity
Aedes aegypti biting peak times
Value
8–12 days
Symbol
—
Quantity
Mosquito extrinsic incubation period
Value
3–14 days (average 5–6)
Symbol
—
Quantity
Human incubation period (dengue)
Value
1 day before fever to 5 days after fever onset
Symbol
—
Quantity
Infectious period (person to mosquito)
Value
<100,000/mm³
Symbol
—
Quantity
Platelet count threshold (DHF diagnosis)
Value
≥20%
Symbol
—
Quantity
Hematocrit rise indicating plasma leakage (DHF)
Important facts
- Dengue 4 serotypes (DENV-1, DENV-2, DENV-3, DENV-4): only one active at a time in a given area (monotypic circulation) or multiple (endemic in Philippines).
- Vector characteristics:
- - Aedes aegypti: anthropophilic (prefers human blood), endophilic (inside homes), DAY-ACTIVE.
- - Aedes albopictus: found in rural/highland areas, also day-active, less urban-adapted.
- Breeding sites (source elimination):
- - Clean stagnant water: flower pots, water storage containers, vases, discarded tires, bottles, coconut shells, bird feeders.
- - NOT in dirty/flowing water (unlike malaria Anopheles).
- Transmission cycle:
- - Viremic person (especially days 1–5) → mosquito bloodmeal → viral replication in mosquito (extrinsic incubation 8–12 days) → mosquito becomes infectious → bites another person.
- - Vertical transmission (mosquito → eggs) is possible but uncommon.
- Clinical presentation:
- - Fever (38–40°C), headache, myalgia, arthralgia, rash (maculopapular, appears after defervescence).
- - Leucopenia, thrombocytopenia common.
- - Dengue hemorrhagic fever (DHF): plasma leakage (hemoconcentration, pleural effusion, ascites), bleeding manifestations, thrombocytopenia (<100,000), shock.
- Warning signs (must seek immediate care):
- - Severe abdominal pain.
- - Persistent vomiting.
- - Bleeding (any manifestation).
- - Lethargy/restlessness.
- - Sudden drop in platelet count.
- - Hematocrit rise (≥20%).
- DOH 4-S Strategy Implementation:
- - Search & Destroy: community mobilization, house-to-house inspection, elimination of water containers, clean gutters.
- - Self-Protection: use of insect repellent (DEET), long sleeves/pants, window screens, bed nets (though dengue is day-biter, nets prevent early morning bites).
- - Seek Early Consultation: educate public on fever >3 days; early detection allows isolation (patient is infectious 1 day before to 5 days after fever onset).
- - Support Fogging/Spraying: only during outbreaks in hotspot barangays; space spraying targets adult mosquitoes; must be repeated every 2–3 days for ≥1 week.
- Notification: dengue is weekly notifiable; outbreak cases reported immediately to trigger response.
- Immunity: primary infection → immunity to that serotype for life; secondary infection with different serotype carries DHF risk.
- No dengue vaccine widely available in Philippines yet (Dengvaxia use restricted to prior-infected persons due to dengue-antibody-dependent enhancement risk).
Key definitions
Dengue
Example
Person infected with DENV-1 → immune to DENV-1 for life; but susceptible to DENV-2, 3, 4 (risk of severe dengue if reinfected).
Viral disease transmitted by Aedes aegypti mosquito; 4 serotypes (DENV-1–4); infection with one serotype gives lifelong immunity to that serotype only.
Aedes aegypti
Example
Unlike Anopheles (night-biter), dengue mosquito bites during daylight; source control targets household water containers.
Urban mosquito vector; DAY-BITER (active 6 AM–6 PM, peaks 8–10 AM & 4–6 PM); breeds in clean STAGNANT WATER (flower pots, water containers, discarded tires).
Dengue Hemorrhagic Fever (DHF) / Dengue Shock Syndrome (DSS)
Example
Person with prior DENV-1 now infected with DENV-2 → DHF/DSS risk due to antibody-dependent enhancement.
Severe form occurring in secondary infection (reinfection with different serotype); characterized by plasma leakage, bleeding, thrombocytopenia, shock.
DOH '4-S' Dengue Strategy
Example
Community: remove water containers (Search-destroy) + wear repellent/long sleeves (Self-protect) → Patient: seek clinic if fever (Early consult) → Health facility: epidemiologic response if outbreak (Support fogging).
Search and destroy, Self-protection, Seek early consultation, Support fogging — integrated vector management & case management.
Diagrams to know
- Aedes aegypti life cycle (egg → larva → pupa → adult) with timeline.
- Dengue transmission cycle: person → mosquito → person, with incubation periods.
- DOH 4-S strategy implementation flowchart.
- Dengue vs. malaria vector comparison (day/night, breeding site, biting behavior, control focus).
Other Endemic Communicable Diseases (Philippine Context)
Common values
Value
Mindanao, Visayas (not Metro Manila)
Symbol
—
Quantity
Malaria endemic zones
Value
8 PM–6 AM (night-biter)
Symbol
—
Quantity
Anopheles mosquito biting time (malaria)
Value
Leyte, Samar, Agusan del Sur
Symbol
—
Quantity
Schistosomiasis endemic provinces
Value
99.9%
Symbol
—
Quantity
Rabies fatality rate (post-symptom)
Value
Within 24 hours (ASAP)
Symbol
—
Quantity
PEP window (rabies)
Value
6 months
Symbol
—
Quantity
Hansen's disease (paucibacillary) MDT duration
Value
12 months
Symbol
—
Quantity
Hansen's disease (multibacillary) MDT duration
Value
5–6 years in endemic areas
Symbol
—
Quantity
Filariasis MDA duration (target)
Important facts
- MALARIA:
- - Endemic in Mindanao and Visayas; not endemic in Metro Manila, Luzon.
- - Vector: Anopheles mosquito (NIGHT-BITER) — bites 8 PM–6 AM.
- - Transmission: blood transfusion, needle-sharing (rare in Philippines).
- - Control: insecticide-treated bed nets (ITNs), indoor residual spraying (IRS), artemisinin-based combination therapy (ACT) for treatment.
- - Clinical: fever, chills, headache, myalgia; can progress to severe malaria (cerebral, renal failure, pulmonary edema).
- SCHISTOSOMIASIS:
- - Endemic in Leyte, Samar, and parts of Mindanao (Agusan del Sur).
- - Parasite: Schistosoma japonicum; intermediate host: Oncomelania snail.
- - Transmission: exposure to freshwater (swimming, wading, bathing) contaminated with cercariae.
- - Pathology: eggs deposit in organs → chronic inflammation, fibrosis, cirrhosis (if liver involved).
- - Control: snail control, water sanitation, mass treatment, health education (avoid infested water).
- FILARIASIS:
- - Endemic in parts of Mindanao, Visayas, and coastal regions.
- - Vectors: Anopheles, Culex, Aedes mosquitoes.
- - Causative agent: Wuchereria bancrofti (lymphatic filariasis).
- - Manifestations: asymptomatic microfilaremia, lymphangitis, lymphadenitis, elephantiasis of limbs/genitalia.
- - Control: Mass Drug Administration (MDA) with albendazole + diethylcarbamazine (DEC) for 5–6 years in endemic areas.
- HANSEN'S DISEASE (LEPROSY):
- - Causative agent: Mycobacterium leprae; chronic, slowly progressive; curable.
- - Transmission: respiratory droplets (prolonged close contact); NOT highly infectious (70–95% of exposed persons are immune).
- - Clinical forms: tuberculoid (few lesions, high immunity), lepromatous (many lesions, low immunity), borderline.
- - Diagnosis: slit-skin smear microscopy (acid-fast bacilli) or clinical features.
- - Treatment: Multidrug Therapy (MDT) for 6–12 months (paucibacillary = 6 months; multibacillary = 12 months).
- - Control: case detection, early treatment, contact screening, DOH Leprosy Program.
- - Complications: reversal reactions, Type 1 & Type 2 reaction (manage with corticosteroids).
- RABIES:
- - Viral disease; ALWAYS FATAL if symptomatic (99.9% fatality rate post-symptom onset).
- - Transmission: saliva of infected animal via bite, scratch, or mucous membrane exposure.
- - Incubation: variable (2 weeks–3 months, rarely up to 1 year); depends on wound location, viral load.
- - Prevention: Post-Exposure Prophylaxis (PEP) with rabies vaccine (PVRV or ERIG + PVRV) MUST be given within 24 hours, ideally within hours of exposure.
- - First aid: wash wound thoroughly with soap & water immediately (removes virus).
- - Animal control: suspect animal observation for 10 days; if animal dies/shows symptoms → confirm rabies.
- - DOH rabies program includes vaccination of high-risk groups (veterinarians, animal handlers).
- DOH ELIMINATION/CONTROL PROGRAMS:
- - Malaria: case management, vector control (ITNs, IRS), surveillance in endemic areas.
- - Schistosomiasis: snail survey & control, sanitation, mass treatment in endemic provinces.
- - Filariasis: MDA programs, surveillance, elimination targets.
- - Leprosy: case detection, MDT provision, disability prevention.
- - Rabies: PEP provision, animal control, vaccination of risk groups.
Key definitions
Malaria
Example
Endemic in Mindanao and Visayas; transmission via NIGHT-FEEDING mosquito; control via bed nets, case management, IRS.
Parasitic disease transmitted by Anopheles mosquito (night-biter); caused by Plasmodium parasites (P. falciparum, P. vivax, P. malariae, P. ovale).
Schistosomiasis (Bilharzia)
Example
Endemic in parts of Visayas (Leyte, Samar) and Mindanao; person wades in infested water → cercariae penetrate skin → chronic inflammation/fibrosis.
Parasitic disease caused by Schistosoma japonicum; transmitted via contact with freshwater containing cercariae; intermediate host is Oncomelania snail.
Filariasis (Lymphatic Filariasis)
Example
Endemic in parts of Mindanao and coastal areas; DOH elimination program uses mass drug administration (MDA).
Parasitic disease transmitted by mosquitoes (Anopheles, Culex, Aedes); caused by Wuchereria bancrofti; characterized by lymphedema, elephantiasis.
Hansen's Disease (Leprosy)
Example
Not eradicated but declining in Philippines; suspect case has skin patch + loss of sensation; treated with MDT (6–12 months depending on classification).
Chronic bacterial disease caused by Mycobacterium leprae; transmitted via respiratory droplets; curable with multidrug therapy (MDT).
Rabies
Example
Dog bite → wash wound immediately + seek PEP (rabies vaccine + rabies immunoglobulin) within 24 hours — before symptoms develop (always fatal if symptomatic).
Fatal viral disease transmitted via saliva (bites, scratches) from infected animals (dogs, bats, monkeys); preventable by post-exposure prophylaxis (PEP) given promptly.
Diagrams to know
- Endemic areas map for malaria, schistosomiasis, filariasis in Philippines.
- Vector-parasite-host relationships for each disease (transmission cycle).
- Rabies post-exposure prophylaxis decision flowchart (animal type, observation status, PEP urgency).
- Hansen's disease classification (tuberculoid vs. lepromatous) based on bacillary load & immunity.
Levels of Prevention in Communicable Disease Control
Important facts
- PRIMARY PREVENTION — specific examples:
- - Immunization (vaccination) is the CLASSIC primary prevention-specific protection (active immunity induced).
- - Health education: hand-washing, food safety, sexual health, tobacco/alcohol cessation.
- - Environmental: clean water, sanitation, vector control (bed nets, IRS for malaria), food storage.
- - Nutrition: malnutrition ↑ TB risk; supplementation improves immunity.
- - Workplace safety: PPE for healthcare workers, needle-stick prevention.
- SECONDARY PREVENTION — examples:
- - Case-finding: sputum screening for TB (smear microscopy, Xpert), dengue surveillance, contact tracing.
- - Screening: TST (tuberculin skin test) for TB infection, blood smear for malaria, stool exam for schistosomiasis.
- - Isolation/quarantine: TB patient during infectious period (first 2 weeks of treatment); close contacts of measles/mumps watched.
- - Contact tracing: find and test contacts of TB, dengue, rabies-exposed persons.
- - Early treatment: DOTS initiation, dengue fluids/transfusion, rabies PEP.
- TERTIARY PREVENTION — examples:
- - TB: monitor treatment response, manage drug side effects (optic neuritis from ethambutol), prevent MDR-TB via adherence.
- - Dengue DHF: aggressive fluid resuscitation, transfusion for hemorrhage, prevent shock.
- - Hansen's disease: MDT adherence, eye care (blindness prevention), physiotherapy (contracture prevention).
- - Malaria: manage severe anemia, cerebral malaria, acute renal failure.
- - Rabies: supportive care only (palliative; always fatal post-symptom) — emphasis is on PEP (secondary prevention).
- VACCINATION IS PRIMARY PREVENTION—SPECIFIC PROTECTION (active immunity).
- PRIMARY PREVENTION INTERRUPTS THE DISEASE CHAIN BEFORE PATHOGEN ENTERS HOST (e.g., immunization, vector control, sanitation).
- SECONDARY PREVENTION DETECTS & TREATS EARLY (e.g., DOTS, case-finding, contact tracing) TO PREVENT TRANSMISSION & PROGRESSION.
Key definitions
Primary Prevention
Example
Vaccination, health education on sanitation, clean water provision, mosquito vector control, nutrition.
Prevent disease BEFORE it occurs in a healthy population; targets susceptible/at-risk individuals.
Secondary Prevention
Example
Case-finding (screening, active surveillance), contact tracing, TB case-finding via sputum screening, early dengue diagnosis, DOTS initiation.
Early detection and PROMPT TREATMENT of disease in early/asymptomatic stages to prevent progression.
Tertiary Prevention
Example
TB patient: monitor drug side effects (ethambutol eye exams) → prevent optic nerve damage; Hansen's patient: physiotherapy → prevent contractures; dengue: manage DHF shock → prevent organ failure.
Limit DISABILITY and REHABILITATE after disease occurs; manage complications, restore function.
Diagrams to know
- Three levels of prevention applied to one disease (e.g., TB: vaccination → case-finding via Xpert → DOTS/drug side effect monitoring).
- Disease progression timeline showing where each prevention level intervenes.
- Disease chain and prevention lever (agent, host, environment, prevention points).
Must remember
EPI Legal Foundation: RA 10152 (2011) mandates FREE routine immunization for all infants/children; Hepatitis B monovalent WITHIN 24 HOURS of birth; Presidential Decree 996 = compulsory immunization <8 years.
Why critical
Exam repeatedly tests legal frameworks for immunization; recall specifics of timing and mandates.
The 6–10–14 Week Schedule is GOLDEN: Pentavalent (DPT–HepB–Hib), OPV, and PCV are given at exactly 6 weeks, 10 weeks, 14 weeks (3 doses each, minimum 4-week interval between doses). This is the backbone of EPI.
Why critical
This is asked in almost every NLE; know the ages, the vaccines, the routes, and the intervals perfectly.
Vaccine Routes & Sites (Non-negotiable):
Why critical
Incorrect route = vaccine failure; students commonly mix these up. BCG = 0.05 mL intradermal (right upper arm); Pentavalent/PCV/IPV = 0.5 mL IM (vastus lateralis); OPV = oral 2–3 drops; Measles/MMR = 0.5 mL SC (outer upper arm).
FIC (Fully Immunized Child) Definition: 1 BCG + 3 OPV + 3 pentavalent (DPT–HepB–Hib) + ≥1 measles vaccine BEFORE 12 months of age. This is the DOH performance indicator; confuse with CIC (by 12–23 months) and you lose marks.
Why critical
Definitions are staple exam questions; FIC vs. CIC vs. CPAB are frequently tested.
Cold Chain Temperatures: RHU = +2°C to +8°C; Regional freezer = −15°C to −25°C. OPV is MOST heat-sensitive (store coldest); DPT/Hep B/Td are FREEZE-SENSITIVE (never freeze). Use the SHAKE TEST for freeze-sensitive vaccines (opaque/clumpy = frozen = discard).
Why critical
Cold chain questions appear in almost every exam; incorrect temperature handling leads to vaccine failure and outbreaks; must know which vaccines freeze-sensitive vs. heat-sensitive.
DOTS = Directly Observed Treatment, Short-course for TB: 5 elements: commitment, diagnosis (Xpert MTB/RIF), standardized regimen with DOT, drug supply, recording/reporting. Category I = 2HRZE/4HR (6 months). Observation is NON-NEGOTIABLE.
Why critical
TB is heavily tested in NLE; DOTS is the cornerstone strategy; missing any element of DOTS or confusing regimens costs marks.
Dengue 4-S Strategy: Search and destroy (breeding sites), Self-protection (repellent, long sleeves), Seek early consultation (fever), Support fogging (hotspots only). Aedes aegypti = day-biter, breeds in clean stagnant water (flower pots, containers, tires). Use repellent & source control, NOT just fogging.
Why critical
Dengue is endemic in Philippines; 4-S is the DOH official strategy; distinguish from malaria control (Anopheles = night-biter, dirty water, ITNs/IRS).
Td for Pregnant Women: Td1 ASAP, Td2 ≥4 weeks later (protects newborn from neonatal tetanus = CPAB status); Td2 also gives ~3 years maternal protection. Td5 = lifetime protection. Two doses minimum for CPAB.
Why critical
Neonatal tetanus prevention is critical; Td scheduling for women is frequently tested; know the minimum (Td2) for CPAB status.
Immediately Notifiable Diseases (within 24 hours): Acute flaccid paralysis (polio), measles, neonatal tetanus, cholera, meningococcal disease, rabies, plague, yellow fever. PIDSR is the reporting system. Failure to report violates RA 9173.
Why critical
Notifiable diseases are exam staples; confusing immediately vs. weekly notifiable costs marks; RA 9173 compliance is tested.
Do NOT Withhold Vaccination for: Mild fever (<38.5°C), mild cough/cold, mild diarrhea, breast-feeding, mild malnutrition, antibiotic use, or recent exposure to disease. Missed opportunities ↓ herd immunity & cause outbreaks. True contraindications are RARE; live vaccines contraindicated only in severe immunosuppression.
Why critical
Students often incorrectly defer vaccination for minor illness; this is a major source of lost marks and real-world vaccine failure.
Last minute tips
Remember the 'Triple Check' for Cold Chain Violations: If a vaccine was left in the sun, in a hot vehicle, or in a freezer (and it's freeze-sensitive), DO NOT USE IT. Use VVM for heat; shake test for freeze. When in doubt, throw it out — vaccine safety is non-negotiable.
When to use
Any question about vaccine storage, handling, or vial condition.
Pentavalent = 5-in-1 (DPT + Hep B + Hib) at 6–10–14 weeks — NOT at birth. BCG and Hep B are separate birth doses. This confusion is a classic trap; Pentavalent is NOT the birth vaccine — HEP B monovalent is.
When to use
Any EPI schedule question; look for the trick of 'when do you give pentavalent?'
For DOTS & TB, Always Ask: 'Is the patient DIRECTLY OBSERVED?' If no observer → NO credit for DOTS; observation is the CORE. Also: Rifampicin = ORANGE-RED urine (NORMAL); ethambutol = optic neuritis (vision loss); streptomycin = hearing loss. Match drug to side effect perfectly.
When to use
Any TB case or DOTS strategy question.
Dengue vs. Malaria Quick Rule: Dengue = DAY-BITER, CLEAN WATER, URBAN (Aedes aegypti); Malaria = NIGHT-BITER, DIRTY WATER, RURAL (Anopheles). If the vector/water/time doesn't match, the disease doesn't match. Also, dengue has 4 serotypes (reinfection risk); malaria has Plasmodium species.
When to use
Any vector-borne disease comparison or endemic disease question.
For Neonatal Tetanus Prevention: Mother with Td1 + Td2 = CPAB newborn (protected). Td2 requires ≥4 weeks after Td1. If mother has NO Td vaccination = newborn is NOT CPAB = neonatal tetanus risk → must give clean delivery, clean cord practices, and watch for signs (lockjaw, opisthotonus by day 3–7 of life).
When to use
Any question about maternal immunization, newborn protection, or neonatal tetanus risk.
Comparison tables
Immunity Types Comparison
| Type | Source of Antibodies | Onset | Duration | Mechanism | Example |
|---|---|---|---|---|---|
| Natural Active | Own body (infection) | Slow (days–weeks) | Lifelong | Immune response to pathogen | Recovering from measles |
| Artificial Active | Vaccine (live/inactivated/toxoid) | Slow (days–weeks) | Years–lifetime | Immune response to vaccine Ag | Measles vaccination |
| Natural Passive | Mother (IgG/breast milk IgA) | Immediate | 6–12 months | Maternal Abs transfer | Newborn with maternal Abs |
| Artificial Passive | IG/antiserum (external source) | Immediate | Weeks–months | Direct Ab administration | Tetanus IG post-exposure |
EPI Vaccine Schedule At-a-Glance
| Age | Vaccine(s) | Route/Dose | Number of Doses |
|---|---|---|---|
| Birth (within 24 hrs) | BCG, Hepatitis B (monovalent) | ID 0.05 mL (BCG); IM 0.5 mL (HepB) | 1 each |
| 6 weeks | Pentavalent, OPV, PCV, IPV (at 14 wks only) | IM 0.5 mL (Penta, PCV); oral 2–3 drops (OPV) | Dose 1 |
| 10 weeks | Pentavalent, OPV, PCV | IM 0.5 mL (Penta, PCV); oral 2–3 drops (OPV) | Dose 2 |
| 14 weeks | Pentavalent, OPV, PCV, IPV | IM 0.5 mL (Penta, PCV, IPV); oral 2–3 drops (OPV) | Dose 3 (Penta, OPV, PCV); Dose 1 (IPV) |
| 9 months | MCV1 (Measles/AMV), IPV | SC 0.5 mL (MCV1); IM 0.5 mL (IPV) | Dose 1 MCV1; Dose 2 IPV |
| 12 months | MMR (MCV2) | SC 0.5 mL | Dose 1 (booster measles) |
Vaccine Route, Site, and Depth of Injection
| Vaccine | Route | Depth | Anatomical Site | Needle Size (gauge) |
|---|---|---|---|---|
| BCG | Intradermal (ID) | Into dermis (45° angle) | Right upper arm/deltoid | 25–26 G |
| Pentavalent, PCV, IPV | Intramuscular (IM) | Into muscle (90° angle) | Vastus lateralis (outer thigh) | 23–25 G |
| OPV | Oral | N/A | Mouth (on tongue) | N/A |
| Measles/MMR | Subcutaneous (SC) | Under skin (45° angle) | Outer upper arm | 25–27 G |
| Hepatitis B (birth) | Intramuscular (IM) | Into muscle (90° angle) | Vastus lateralis | 23–25 G |
Cold Chain Temperature Requirements
| Storage Level | Temperature Range | Storage Equipment | Vaccines Stored Here | Monitoring |
|---|---|---|---|---|
| Manufacturer/Central | −15°C to −25°C | Ultra-cold freezer | OPV, Measles (bulk stock) | Continuous, automated alarm |
| Regional/Provincial | −15°C to −25°C | Freezer | OPV, Measles stock | Twice daily; temperature log |
| Health Center/RHU | +2°C to +8°C | Refrigerator (2–8°C) | All vaccines (Pentavalent, BCG, Td, PCV, IPV, etc.) | Twice daily; thermometer & log |
| Outreach/Mobile Clinic | +2°C to +8°C | Vaccine cooler with ice packs | Day's supply of vaccines | Thermometer in cooler; FEFO |
Freeze-Sensitive vs. Heat-Sensitive Vaccines
| Vaccine Type | Temperature Sensitivity | Storage Constraint | Detection Method | Action if Compromised | |
|---|---|---|---|---|---|
| DPT, Pentavalent, Hepatitis B, Td | Freeze-sensitive | Must NOT be frozen (−15°C or below destroys) | Keep at +2°C to +8°C (middle shelf of fridge) | Shake test (opaque/clumpy = frozen) | Discard immediately; do NOT use |
| OPV | Both freeze-sensitive AND heat-sensitive | Most vulnerable; store in coldest section | Use shake test for freeze; check VVM for heat | Shake test & VVM check | Discard if frozen or VVM reached |
| Measles, BCG | Heat-sensitive (more than freeze-sensitive) | Protect from heat/light; store in freezer at −15 to −25°C (central) or coldest part of RHU fridge | VVM color change, avoid sunlight | VVM indicator on vial | Discard if VVM exceeds alert line |
| IPV, PCV | Moderately heat-sensitive | Store at +2°C to +8°C; protect from heat | VVM for heat; not freeze-sensitive so IM can tolerate brief freezing | VVM check | Discard if VVM unsafe |
TB Treatment Categories & Regimens
| Category | Patient Type | Regimen | Intensive Phase | Continuation Phase | Total Duration |
|---|---|---|---|---|---|
| Category I | New TB (smear +/−, extra-pulmonary) | 2HRZE/4HR | 2 months HRZE daily | 4 months HR daily | 6 months |
| Category II | Previously treated (relapse, failure, lost) | 2HRZES/1HRZE/5HRE | 2 months HRZES + 1 month HRZE | 5 months HRE (or alternative) | 8 months |
| MDR-TB | Rifampicin-resistant or multi-drug resistant | Second-line drugs (fluoroquinolone, injectable, others) | ~6–8 months with second-line | ~12–18 months continuation | 18–24 months (PMDT) |
Anti-TB Drugs: Mechanism, Side Effects, Monitoring
| Drug (Code) | Generic Name | Major Side Effect(s) | Monitoring Required | Patient Education |
|---|---|---|---|---|
| H | Isoniazid | Hepatotoxicity, peripheral neuropathy | LFT baseline & monthly; ask about jaundice, abdominal pain | Report dark urine, nausea; take on empty stomach; do NOT miss doses |
| R | Rifampicin | Hepatotoxicity, discolors body fluids (orange-red urine/tears/sweat) | LFT baseline & monthly; ask about jaundice, dark urine | NORMAL to have orange-red urine/tears (warn patient to prevent panic); take on empty stomach |
| Z | Pyrazinamide | Hepatotoxicity, hyperuricemia (gout-like), arthralgia | LFT baseline & monthly; uric acid; joint pain assessment | Report yellow eyes; monitor joint pain (may mimic gout); take with food if GI upset |
| E | Ethambutol | Optic neuritis (color blindness, vision loss, red-green vision affected) | Vision assessment at baseline, monthly (color vision test); ask re: blurred vision, color changes | Report any vision changes immediately (red-green color loss earliest sign); avoid daily doses >25 mg/kg |
| S | Streptomycin | Ototoxicity (hearing loss, vertigo), nephrotoxicity | Baseline & monthly audiometry; assess vertigo, tinnitus; renal function (creatinine); IM injection site | Report hearing loss or dizziness; injections may cause pain at site; high-frequency hearing loss first |
Immediately Notifiable vs. Weekly Notifiable Diseases
| Reporting Timeframe | Example Diseases | Trigger Action | Reporting Route |
|---|---|---|---|
| Immediately (within 24 hours) | Acute flaccid paralysis, measles, neonatal tetanus, cholera, meningococcal disease, rabies, plague, yellow fever | Outbreak investigation, emergency response, contact tracing, mass vaccination campaign | Health worker → RHU/facility → City Health Office → DOH (via hotline/email) |
| Weekly Notifiable | Dengue, typhoid, dysentery, TB, diarrheal disease, respiratory infections | Trend surveillance, resource allocation, program evaluation | Health facility → RHU → CHO → PHO → DOH (aggregate report) |
Vector Comparison: Anopheles vs. Aedes aegypti
| Characteristic | Anopheles (Malaria) | Aedes aegypti (Dengue) |
|---|---|---|
| Biting Activity | Night-biter (8 PM–6 AM) | Day-biter (6 AM–6 PM, peaks 8–10 AM & 4–6 PM) |
| Breeding Sites | Dirty/stagnant water (marshes, rice paddies, puddles) | Clean stagnant water (flower pots, water containers, discarded tires, bottles) |
| Habitat | Rural, highland, lowland areas (Mindanao, Visayas) | Urban, periurban environments (everywhere in Philippines) |
| Host Preference | Less selective (zoophilic in some areas) | Highly anthropophilic (prefers human blood) |
| Vector Control | ITNs (bed nets), IRS (indoor residual spraying), drainage of breeding sites | Source elimination (remove water containers), Self-protection (repellent, clothing), Fogging/spraying during outbreak |
Diagrams
Communicable Disease Control & Immunization Overview
Comprehensive mind map showing all major topics in the chapter, organized by immunity concepts, EPI program, vaccination schedules, disease-specific control programs, and prevention levels. Serves as a visual roadmap of the entire chapter.
EPI Infant Vaccination Schedule Timeline (Birth to 12 Months)
Detailed timeline flowchart of the complete EPI schedule from birth to 12 months, showing exact ages, vaccines given at each visit, and decision point for FIC status. Visually emphasizes the 6–10–14 week backbone and the 9–12 month measles doses.
Should This Child Be Vaccinated? Decision Tree
Decision tree flowchart for healthcare workers to determine vaccination eligibility. Emphasizes that MOST children CAN be vaccinated; true contraindications are rare. Distinguishes between conditions that warrant deferral vs. those that don't.
TB Diagnosis & DOTS Treatment Pathway (Category I)
Comprehensive flowchart of TB case management from presumptive diagnosis through Xpert MTB/RIF, treatment categorization, DOTS phases, and outcome assessment. Highlights the sputum monitoring checkpoints and criteria for cure.
Dengue Surveillance & Response (DOH 4-S Strategy)
Flowchart showing dengue case detection, severity assessment, patient management, and DOH 4-S control strategy response. Illustrates the link between individual case management and community-level outbreak response.
Vaccine Cold Chain Temperature Zones & Vaccine Placement
State diagram showing the entire cold chain from manufacturer through to child vaccination, with temperature requirements and key actions at each stage. Emphasizes temperature maintenance and monitoring requirements.
Distribution of First-Line Anti-TB Drugs in Category I Regimen
Pie chart showing the composition of Category I TB regimen: all 4 drugs (HRZE) during intensive phase (months 0–2), then only HR during continuation phase (months 2–6). Visual representation of how Z and E are discontinued after the intensive phase.
Tetanus (Td) Vaccination Schedule for Women & Protection Timeline
Timeline showing the complete Td vaccination schedule for women, with emphasis on the protection duration gained at each dose. Highlights the critical Td2 milestone that confers CPAB status and neonatal tetanus protection.
Levels of Prevention Applied to TB Control
Comprehensive flowchart showing how the three levels of prevention (primary, secondary, tertiary) apply specifically to TB control, with examples at each level converging toward the elimination goal. Illustrates the integrated approach to disease control.