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Midwife Licensure Exam Community & Public HealthCommunicable Disease Control & ImmunizationRevision Notes

Final-week revision notes for Communicable Disease Control & Immunization. If you have already studied the full chapter, this page is your go-to refresher before sitting the Midwife Licensure Exam. Compact, high-yield, and aligned with what Professional Regulation Commission (PRC) — Board of Midwifery tests in the Community & Public Health subtest.

Exam context

For the Midwife Licensure Examination, Professional Regulation Commission (PRC) — Board of Midwifery tests Community & Public Health under a "Core" label, with Communicable Disease Control & Immunization in the 4th slot across 6 chapters. Midwife Licensure Exam candidates must clear the 75% weighted average cut on the 2026 paper, which draws about a meaningful share of Community & Public Health questions. Date to watch: April and November 2026 (expected).

Communicable Disease Control & Immunization - Revision Notes

Communicable disease control is one of the most heavily tested areas of the NLE Board Examination in Community Health Nursing (CHN). As a community health nurse functioning under RA 9173 (Philippine Nursing Act of 2002), you are a frontline defender against vaccine-preventable diseases, tuberculosis, dengue, and other endemic infections. This chapter covers the Expanded Program on Immunization (EPI), DOTS/NTP, dengue control, notifiable disease reporting, and the levels of prevention — all anchored in the Philippine Department of Health (DOH) programs and policies. Master these concepts and you will be well-equipped for both the NLE and actual community nursing practice.

Sections

Exam Tips

  • When the NLE stem asks 'what level of prevention is immunization?' — always answer PRIMARY prevention, specifically SPECIFIC PROTECTION.
  • Contact tracing in TB = SECONDARY prevention (early case detection).
  • Physiotherapy for post-polio = TERTIARY prevention (rehabilitation).
  • Remember: Primary = Before disease; Secondary = Early in disease; Tertiary = After disability.

Key Points

  • Primary prevention prevents disease BEFORE it occurs — this is the community nurse's most powerful tool.
  • Primary prevention includes: health education, immunization, sanitation, safe water supply, vector control, and adequate nutrition.
  • Immunization is the classic example of PRIMARY prevention under the category of SPECIFIC PROTECTION (Leavell and Clark model).
  • Secondary prevention involves EARLY DETECTION and PROMPT TREATMENT — case-finding, screening programs, contact tracing, and early diagnosis.
  • Tertiary prevention focuses on LIMITATION OF DISABILITY and REHABILITATION — managing complications and reintegrating recovered patients into the community.
  • In Maslow's hierarchy, primary prevention safeguards physiological and safety needs before threats materialize.
  • The nursing process aligns with levels of prevention: Assessment/Diagnosis drives secondary; Planning/Implementation spans all three levels.

Definitions

Term

Primary Prevention

Definition

Actions taken to prevent the occurrence of disease in a healthy population. Includes health promotion and specific protection strategies such as immunization, sanitation, and vector control.

Importance

NLE FAVORITE — always identify immunization as PRIMARY prevention/specific protection. Do not confuse with secondary prevention.

Term

Secondary Prevention

Definition

Early diagnosis and prompt treatment to halt the progression of disease. Includes mass screening, case-finding, contact tracing, and early treatment programs.

Importance

Case-finding in TB (sputum microscopy) and dengue surveillance are classic secondary prevention examples tested in NLE.

Term

Tertiary Prevention

Definition

Measures that limit the degree of disability and promote rehabilitation in patients who already have established disease and its sequelae.

Importance

Disability limitation and rehabilitation — e.g., physiotherapy for post-polio residual paralysis or management of TB complications.

Term

Herd Immunity

Definition

Indirect protection that occurs when a sufficiently high proportion of a population has become immune to an infection (through vaccination or prior infection), thereby reducing the likelihood of infection for individuals who lack immunity.

Importance

Key concept for justifying mass immunization campaigns. When herd immunity threshold is reached, even unvaccinated individuals gain protection.

Section Title

Levels of Prevention in Communicable Disease

Common Mistakes

  • Confusing immunization (primary prevention) with early diagnosis (secondary prevention) — immunization PREVENTS disease; it does not detect it.
  • Placing DOTS/TB treatment under primary prevention — treatment is SECONDARY prevention (early diagnosis and prompt treatment).
  • Forgetting that tertiary prevention includes rehabilitation, not just treatment of complications.
  • Confusing 'specific protection' (immunization) with 'health promotion' — both are under primary prevention but are different sub-levels.

Exam Tips

  • Vaccine/toxoid = ACTIVE immunity (artificial). Immunoglobulin/antiserum = PASSIVE immunity (artificial).
  • Placenta/breast milk = PASSIVE immunity (natural).
  • If an NLE question asks about 'immediate but temporary' protection — answer: PASSIVE immunity.
  • If an NLE question asks about 'long-lasting' protection from a vaccine — answer: ACTIVE immunity.

Key Points

  • Active immunity means the individual's own immune system produces antibodies — it is LONG-LASTING.
  • Natural active immunity results from recovering from an actual infection (e.g., natural measles infection).
  • Artificial active immunity results from vaccines and toxoids (e.g., BCG vaccine, MMR vaccine) — this is what EPI provides.
  • Passive immunity means antibodies are RECEIVED from another source — it is IMMEDIATE but TEMPORARY.
  • Natural passive immunity: maternal IgG antibodies cross the placenta; IgA from breast milk protects the newborn.
  • Artificial passive immunity: immunoglobulins/antisera given to an exposed person (e.g., anti-rabies immunoglobulin, tetanus immunoglobulin).
  • KEY DISTINCTION: Vaccines → active immunity (slow onset, long duration). Immunoglobulins → passive immunity (immediate onset, short duration).
  • Toxoids are inactivated bacterial toxins that stimulate active immunity (e.g., tetanus toxoid, diphtheria toxoid in Td vaccine).

Definitions

Term

Active Immunity

Definition

Immunity produced by the individual's own immune system following exposure to an antigen, either naturally (infection) or artificially (vaccine/toxoid). Characterized by memory B and T cells, making it long-lasting.

Importance

All EPI vaccines produce ACTIVE immunity. Key NLE concept — distinguish from passive immunity.

Term

Passive Immunity

Definition

Immunity conferred by the transfer of pre-formed antibodies from another individual or source. Does NOT involve the recipient's immune system producing antibodies. Immediate but temporary (weeks to months).

Importance

Anti-rabies immunoglobulin, tetanus immunoglobulin, and maternal antibodies in breast milk are examples of passive immunity. NLE may test whether a given intervention is active or passive.

Term

Toxoid

Definition

A bacterial toxin that has been chemically modified (detoxified) to eliminate its harmful properties while retaining its ability to stimulate an immune response. Examples: tetanus toxoid, diphtheria toxoid.

Importance

Toxoids are classified under artificial active immunity — a common NLE question differentiates toxoids from vaccines.

Section Title

Immunity Types and Concepts

Common Mistakes

  • Saying that breast milk gives the infant 'active' immunity — breast milk (IgA) gives NATURAL PASSIVE immunity.
  • Confusing anti-rabies vaccine (active immunity) with anti-rabies immunoglobulin (passive immunity) — both are given post-exposure but they are different types.
  • Thinking passive immunity is 'better' because it is immediate — passive immunity is TEMPORARY; active immunity is long-lasting.
  • Forgetting that toxoids produce ACTIVE immunity — they are not passive just because they come from bacteria.

Exam Tips

  • ROUTES MEMORY AID: BCG = Intradermal | OPV = Oral | MMR/Measles = Subcutaneous | Pentavalent/PCV/IPV/HepB = Intramuscular.
  • 6-10-14 WEEKS vaccines: Pentavalent + OPV + PCV (all three, all together, all 3 doses).
  • 9 MONTHS vaccines: MCV1 (measles/MMR) AND IPV 2nd dose.
  • 12 MONTHS: MCV2 (MMR 2nd dose) — MMR given TWICE: at 9 months and 12 months.
  • BIRTH vaccines: BCG (intradermal 0.05 mL) and Hepatitis B monovalent (IM 0.5 mL within 24 hours).
  • EPI = 1976; RA 10152 = 2011 — memorize both years.
  • Classic 6 EPI diseases: TB, Diphtheria, Pertussis, Tetanus, Polio, Measles — 'TDP-TPM'.
  • Never withhold vaccines for minor illness (mild cough, low-grade fever, mild diarrhea) — missed opportunities lower coverage.

Key Points

  • EPI was launched by DOH in 1976 to reduce morbidity and mortality from vaccine-preventable diseases.
  • Legal basis: Presidential Decree 996 (compulsory immunization for children under 8) and RA 10152 — Mandatory Infants and Children Health Immunization Act of 2011 (mandates FREE routine immunization).
  • Original 6 target diseases (memorize!): Tuberculosis, Diphtheria, Pertussis (whooping cough), Tetanus, Poliomyelitis, and Measles. Mnemonic: 'TD-PT-PM' or 'The Dirty Poor Town People Missed.'
  • The program has EXPANDED to include Hepatitis B, Haemophilus influenzae type b (Hib), Pneumococcal disease, and others.
  • BCG and Hepatitis B monovalent are given AT BIRTH.
  • Pentavalent (DPT-HepB-Hib), OPV, and PCV follow the 6-10-14 WEEKS schedule (3 doses each).
  • IPV (inactivated polio) is given at 14 WEEKS and 9 MONTHS (2 doses total).
  • MCV1 (measles-containing vaccine or MMR) at 9 MONTHS; MCV2 (MMR) at 12 MONTHS.
  • Fully Immunized Child (FIC): receives all antigens BEFORE 12 months of age.
  • Completely Immunized Child (CIC): completes immunization at 12-23 months of age.
  • Child Protected at Birth (CPAB): newborn protected from neonatal tetanus through maternal Td immunization.

Definitions

Term

Fully Immunized Child (FIC)

Definition

A child who has received 1 dose BCG, 3 doses OPV, 3 doses Pentavalent (DPT-HepB-Hib), 3 doses PCV, 2 doses IPV, and at least 1 dose measles-containing vaccine (MCV1), ALL completed BEFORE reaching 12 months (first birthday) of age.

Importance

FIC is a critical DOH indicator for immunization coverage. NLE frequently tests the distinction between FIC (before 12 months) and CIC (12-23 months).

Term

Pentavalent Vaccine (DPT-HepB-Hib)

Definition

A combined vaccine that protects against five diseases: Diphtheria, Pertussis (whooping cough), Tetanus, Hepatitis B, and Haemophilus influenzae type b. Given intramuscularly at 6, 10, and 14 weeks.

Importance

One injection, five diseases — the most complex vaccine in the schedule. NLE tests the schedule (6-10-14 weeks), route (IM), site (vastus lateralis), and dose (0.5 mL).

Term

BCG (Bacillus Calmette-Guerin) Vaccine

Definition

A live attenuated vaccine derived from Mycobacterium bovis that provides protection against severe forms of tuberculosis (especially TB meningitis and miliary TB in children). Given intradermally (0.05 mL) at the right upper arm/deltoid at birth.

Importance

BCG route and dose are classic NLE questions: INTRADERMAL, 0.05 mL for infants. A successful BCG vaccination produces a wheal that later forms a small scar.

Term

RA 10152 — Mandatory Infants and Children Health Immunization Act of 2011

Definition

Philippine law that mandates FREE routine immunization for infants and children, including Hepatitis B vaccine within 24 hours of birth. This law expanded the EPI and strengthened the state's obligation to provide immunization services.

Importance

Know this law for NLE — it is the current legal mandate for EPI and mandates the birth dose of Hepatitis B within 24 hours.

Term

Koch's Phenomenon (PPD Reaction)

Definition

An accelerated local reaction at the BCG injection site occurring within 48-72 hours, indicating the individual has had prior TB exposure or infection. This is a normal immune response and does not mean the vaccine caused TB.

Importance

NLE may describe an accelerated reaction after BCG and ask the nurse to interpret it — this indicates PRIOR TB sensitization, not a vaccine complication.

Section Title

Expanded Program on Immunization (EPI)

Common Mistakes

  • Saying BCG is given IM — BCG is strictly INTRADERMAL (not IM, not SC).
  • Confusing the dose: BCG for infants is 0.05 mL (NOT 0.1 mL — that is for older children).
  • Saying MMR/measles is given IM — MCV1 and MMR (MCV2) are SUBCUTANEOUS.
  • Forgetting that IPV has 2 doses in the current DOH schedule: at 14 WEEKS and 9 MONTHS.
  • Saying FIC is completed by 18 months — FIC must be completed BEFORE 12 months. After 12 months = CIC.
  • Confusing PD 996 (compulsory immunization) with RA 10152 (mandatory free immunization) — know both.
  • Forgetting to include PCV in the FIC criteria — the current EPI schedule includes PCV at 6-10-14 weeks.
  • Giving live vaccines (BCG, MMR, OPV) to severely immunocompromised children — this is a TRUE contraindication.

Exam Tips

  • For NLE: When a question asks about the site of IM injection in an infant — always say VASTUS LATERALIS.
  • Three vaccines at once at 6, 10, and 14 weeks: Pentavalent + OPV + PCV.
  • Polio has BOTH OPV (oral, 3 doses) AND IPV (injectable, 2 doses) in the current schedule — a total of 5 polio vaccine doses.
  • Vaccine given at the MOST visits from 6-14 weeks: Pentavalent, OPV, and PCV (3 vaccines at 3 visits).

Key Points

  • BIRTH: BCG (intradermal, right upper arm, 0.05 mL) and Hepatitis B monovalent (IM, vastus lateralis, 0.5 mL, within 24 hours).
  • 6 WEEKS: Pentavalent 1st dose (IM, 0.5 mL) + OPV 1st dose (oral, 2-3 drops) + PCV 1st dose (IM, 0.5 mL).
  • 10 WEEKS: Pentavalent 2nd dose + OPV 2nd dose + PCV 2nd dose.
  • 14 WEEKS: Pentavalent 3rd dose + OPV 3rd dose + PCV 3rd dose + IPV 1st dose (IM, 0.5 mL).
  • 9 MONTHS: MCV1 — measles-containing vaccine or MMR (subcutaneous, 0.5 mL, outer upper arm) + IPV 2nd dose (IM).
  • 12 MONTHS: MCV2 — MMR (subcutaneous, 0.5 mL).
  • Minimum interval between doses in a series: 4 WEEKS (28 days) for Pentavalent, OPV, and PCV.
  • SITE for IM injections in infants: VASTUS LATERALIS (anterolateral thigh) — not the deltoid (too small in infants).
  • SITE for BCG: Right upper arm (deltoid region) — INTRADERMAL only.
  • SITE for SC vaccines (MMR): Outer upper arm.

Definitions

Term

OPV (Oral Polio Vaccine)

Definition

A live attenuated oral vaccine given as 2-3 drops by mouth. Provides intestinal mucosal immunity and is most effective against wild poliovirus transmission. Given at 6, 10, and 14 weeks. Most heat-sensitive vaccine in the EPI.

Importance

OPV is the MOST HEAT-SENSITIVE vaccine — store it at the coldest part of the refrigerator. NLE tests both the schedule and the cold chain sensitivity.

Term

IPV (Inactivated Polio Vaccine)

Definition

An injectable, killed poliovirus vaccine that provides systemic humoral immunity. In the current Philippine EPI, IPV is given at 14 weeks and 9 months (2 doses), given intramuscularly at 0.5 mL. Safe for immunocompromised individuals (killed vaccine).

Importance

NLE tests the difference between OPV (oral, live, given at 6-10-14 weeks) and IPV (injectable, killed, given at 14 weeks and 9 months).

Term

PCV (Pneumococcal Conjugate Vaccine)

Definition

A vaccine that protects against Streptococcus pneumoniae, which causes pneumonia, meningitis, and bacteremia. Given intramuscularly at 6, 10, and 14 weeks (3 doses) in the Philippine EPI. Dose: 0.5 mL.

Importance

PCV follows the same 6-10-14 week schedule as Pentavalent and OPV. Remember it as one of the three vaccines given simultaneously at 6, 10, and 14 weeks.

Section Title

EPI Immunization Schedule (Detailed Reference Table)

Common Mistakes

  • Giving IM injections to infants in the deltoid — use VASTUS LATERALIS for infants.
  • Confusing the number of OPV doses (3 doses: 6-10-14 weeks) with the number of IPV doses (2 doses: 14 weeks and 9 months).
  • Thinking the minimum interval between Pentavalent doses is 6 weeks — the MINIMUM is 4 WEEKS (28 days).
  • Administering BCG subcutaneously or IM — BCG MUST be intradermal. If given SC/IM, a local abscess may form.

Exam Tips

  • NLE MEMORY AID for Td duration: Td2 = 3 years, Td3 = 5 years, Td4 = 10 years, Td5 = Lifetime. Think: '3-5-10-Life'.
  • Td2 = the magical dose — protects both mother and newborn from tetanus.
  • CPAB indicator is achieved when mother has at least Td2 and baby is born.
  • Td minimum intervals: Td1→Td2: 4 weeks | Td2→Td3: 6 months | Td3→Td4: 1 year | Td4→Td5: 1 year.

Key Points

  • Goal: Eliminate MATERNAL AND NEONATAL TETANUS — a major cause of newborn deaths in developing countries.
  • Td vaccine (Tetanus-Diphtheria toxoid) has replaced the older TT (Tetanus Toxoid) in the Philippine EPI.
  • Td1: Given as early as possible in pregnancy or to women of childbearing age — gives NO immediate protection.
  • Td2: At least 4 WEEKS after Td1 — gives approximately 3 YEARS of protection; PROTECTS THE NEWBORN FROM NEONATAL TETANUS.
  • Td3: At least 6 MONTHS after Td2 — gives approximately 5 YEARS of protection.
  • Td4: At least 1 YEAR after Td3 — gives approximately 10 YEARS of protection.
  • Td5: At least 1 YEAR after Td4 — gives LIFETIME protection.
  • A woman who has completed all 5 doses is considered permanently protected.
  • Child Protected at Birth (CPAB): newborn whose mother has received at least Td2 during or before the pregnancy — protected from neonatal tetanus.
  • Minimum interval for Td2 protection: 4 WEEKS after Td1 — and Td2 must be given at least 2-3 WEEKS BEFORE DELIVERY for maternal antibodies to transfer.

Definitions

Term

Neonatal Tetanus

Definition

Tetanus occurring in newborns, typically due to infection through the unclean cutting of the umbilical cord. Characterized by inability to suck, muscle stiffness, and spasms. Preventable through maternal Td immunization and clean delivery practices.

Importance

A DOH priority — maternal Td2 is the key intervention. NLE tests the Td schedule and the concept of CPAB.

Term

Child Protected at Birth (CPAB)

Definition

A newborn who is protected from neonatal tetanus because the mother received at least 2 doses of Td (or TT) vaccine, with the 2nd dose given at least 2 weeks before delivery, providing passive transfer of maternal antibodies.

Importance

CPAB is a key DOH immunization indicator. NLE frequently asks which Td dose protects the newborn — the answer is TD2 (2nd dose).

Section Title

Tetanus (Td) Immunization for Women of Childbearing Age

Common Mistakes

  • Saying Td1 gives protection — Td1 gives NO protection. Protection begins with Td2.
  • Forgetting the minimum interval: Td1 to Td2 = at least 4 WEEKS (NOT just 'next visit').
  • Confusing TT (tetanus toxoid) with Td (tetanus-diphtheria) — the current program uses Td, which also protects against diphtheria.
  • Thinking 5 doses protect for only 10 years — Td5 gives LIFETIME protection.
  • Forgetting that Td2 gives approximately 3 years of protection (not lifetime).

Exam Tips

  • COLD CHAIN TEMPERATURE AID: Health center = +2°C to +8°C | Regional freezer = -15°C to -25°C.
  • HEAT-SENSITIVE (store coldest): OPV > Measles > BCG. Think: 'OMB — store them coldest.'
  • FREEZE-SENSITIVE (never freeze): DPT, Hep B, Td, Pentavalent. Think: 'Frozen DPT is dead.'
  • VVM: Inner darker than outer = DISCARD. Inner lighter = SAFE to use.
  • Shake test = for freeze-sensitive vaccines (to check if accidentally frozen).
  • FEFO = first expiry, first out — always use the one expiring soonest first.

Key Points

  • The COLD CHAIN is the system of storing and transporting vaccines within the safe temperature range from manufacturer to the child — any break in the cold chain can destroy vaccine potency.
  • HEALTH CENTER/RHU refrigerator temperature: +2°C to +8°C (the standard working temperature for vaccine storage).
  • REGIONAL/PROVINCIAL LEVEL freezers: -15°C to -25°C (for storing OPV and measles vaccine stocks longer-term).
  • MOST HEAT-SENSITIVE vaccines (store where it is COLDEST): OPV (most sensitive) > Measles/MMR > BCG.
  • FREEZE-SENSITIVE vaccines (must NEVER be frozen — store in the BODY of the refrigerator, NOT the freezer): DPT, Hepatitis B, Td, and Pentavalent. Freezing destroys their potency.
  • The SHAKE TEST detects whether a freeze-sensitive vaccine has been frozen: shake the vial and observe — if a precipitate forms and does NOT redissolve (compared to a known good control), the vaccine has been damaged and must be discarded.
  • FEFO principle: 'First Expiry, First Out' — always use the vaccine with the earliest expiry date first to prevent waste.
  • Vaccine Vial Monitor (VVM): a heat-sensitive label on vaccine vials that changes color when the vaccine has been exposed to excessive heat, indicating it may no longer be potent.
  • The inner square of the VVM changing color DARKER than the outer circle = vaccine should NOT be used.
  • Cold chain equipment at the health center: refrigerators (for +2 to +8°C storage) and cold boxes/vaccine carriers with ice packs (for transport).

Definitions

Term

Cold Chain

Definition

The uninterrupted system of refrigeration and temperature-controlled storage that ensures vaccines maintain their potency from the point of manufacture to the point of administration. Any break in the cold chain (exposure to extreme heat or freezing) can render vaccines ineffective.

Importance

A major NLE topic — nurses at the RHU are responsible for maintaining the cold chain. Questions test temperature ranges, heat-sensitive vs. freeze-sensitive vaccines, and the shake test.

Term

Vaccine Vial Monitor (VVM)

Definition

A small label attached to a vaccine vial that changes color (darkens) when the vaccine has been exposed to excessive cumulative heat. The VVM indicates heat exposure — if the inner square is darker than or matches the outer circle, the vaccine must not be used.

Importance

NLE tests VVM interpretation. DARK inner square = do NOT use the vaccine.

Term

Shake Test

Definition

A test performed to detect whether freeze-sensitive vaccines (DPT, Hepatitis B, Td, Pentavalent) have been accidentally frozen. The suspected vial is shaken and observed: if a flocculate (precipitate) forms and does not redissolve, the vaccine has been freeze-damaged and must be discarded.

Importance

Freezing destroys adsorbed vaccines. The shake test is the standard field method to detect freeze damage. NLE may ask what test to perform when a vaccine is suspected of being frozen.

Term

FEFO (First Expiry, First Out)

Definition

A stock management principle where vaccines (or any supplies) with the earliest expiration dates are used first, minimizing wastage of vaccine stocks.

Importance

FEFO is the principle for stock rotation in the EPI cold chain — a standard NLE and practical nursing knowledge point.

Section Title

The Cold Chain System

Common Mistakes

  • Putting DPT or Hepatitis B in the FREEZER — freeze-sensitive vaccines must NEVER be frozen; they belong in the refrigerator body at +2 to +8°C.
  • Confusing the most heat-sensitive vaccine (OPV) with a freeze-sensitive vaccine — OPV is HEAT-sensitive (not freeze-sensitive; it IS stored in the freezer at regional level).
  • Using the wrong VVM interpretation: a LIGHTER inner square means the vaccine is still good; a DARKER inner square means it is compromised.
  • Forgetting FEFO — using vaccines closest to the front (not expiry date) is a common real-world mistake.
  • Thinking the shake test is for all vaccines — it is specifically for FREEZE-SENSITIVE vaccines (DPT, Hep B, Td, Pentavalent).

Exam Tips

  • DOTS mnemonic for 5 elements: 'P-C-S-U-R' — Political commitment, Case detection, Standardized treatment, Uninterrupted supply, Recording/Reporting.
  • Drug side effects to MEMORIZE: Rifampicin = orange urine (NORMAL), hepatotoxicity | Isoniazid = peripheral neuropathy (give Vit B6), hepatotoxicity | Ethambutol = optic neuritis (color vision changes) | Streptomycin = ototoxicity (hearing loss), nephrotoxicity | Pyrazinamide = hyperuricemia (gout), hepatotoxicity.
  • Category I = NEW cases = 2HRZE/4HR = 6 months total.
  • Category II = PREVIOUSLY TREATED = longer regimen with Streptomycin added.
  • GeneXpert is PRIMARY diagnostic; DSSM used for follow-up monitoring.
  • Treatment partner in DOTS can be a family member, barangay health worker, or neighbor — someone the patient trusts and lives near.

Key Points

  • TB remains a major public health problem in the Philippines — the NTP uses DOTS (Directly Observed Treatment, Short-course) as its cornerstone strategy.
  • DOTS means a health worker or designated treatment partner PHYSICALLY WATCHES the patient SWALLOW EVERY DOSE of anti-TB medication — this is non-negotiable.
  • The FIVE ELEMENTS of DOTS: 1) Political commitment with sustained financing, 2) Case detection through quality-assured bacteriology, 3) Standardized treatment with DIRECT OBSERVATION, 4) Uninterrupted supply of quality-assured anti-TB drugs, 5) Standardized recording and reporting system.
  • PRIMARY DIAGNOSTIC TOOL: Xpert MTB/RIF (GeneXpert) — rapid, also detects rifampicin resistance. Direct Sputum Smear Microscopy (DSSM) is used for treatment monitoring/follow-up.
  • First-line anti-TB drugs (HRZE-S mnemonic): H = Isoniazid, R = Rifampicin, Z = Pyrazinamide, E = Ethambutol, S = Streptomycin.
  • Treatment has an INTENSIVE PHASE (~2 months) and a CONTINUATION PHASE (~4 months).
  • Category I (NEW TB cases): 2HRZE / 4HR — 2 months HRZE (intensive) then 4 months HR (continuation).
  • Category II (PREVIOUSLY TREATED cases — relapse, failure, after loss to follow-up): 2HRZES / 1HRZE / 5HRE.
  • MDR-TB (Multi-Drug Resistant TB) is managed under PMDT (Programmatic Management of Drug-Resistant TB).
  • BCG vaccine provides primary prevention against SEVERE FORMS of childhood TB (TB meningitis, miliary TB) but does NOT prevent adult pulmonary TB or TB infection.

Definitions

Term

DOTS (Directly Observed Treatment, Short-course)

Definition

The internationally recognized strategy for TB control in which a health worker or treatment partner directly watches and confirms that the TB patient swallows every dose of anti-TB medication. This ensures adherence, prevents drug resistance, and is the core of the Philippine NTP.

Importance

The single most important NLE concept in the TB section. DOTS = watching the patient SWALLOW every dose. Not just dispensing — actually observing.

Term

Category I Treatment (2HRZE/4HR)

Definition

The standard treatment regimen for new TB cases (new smear-positive pulmonary TB, new smear-negative pulmonary TB, extrapulmonary TB). Intensive phase: 2 months of Isoniazid (H) + Rifampicin (R) + Pyrazinamide (Z) + Ethambutol (E). Continuation phase: 4 months of Isoniazid (H) + Rifampicin (R).

Importance

Category I = first-time TB treatment. NLE tests the drug regimen and phase durations. Remember: total 6 months.

Term

Xpert MTB/RIF (GeneXpert)

Definition

A rapid molecular diagnostic test for TB that detects Mycobacterium tuberculosis DNA and simultaneously identifies rifampicin resistance within approximately 2 hours. It is now the PRIMARY first-line diagnostic tool in the Philippine NTP, replacing sputum microscopy as the initial test.

Importance

NLE is updating to reflect GeneXpert as the primary diagnostic tool. Know that it detects BOTH TB and rifampicin resistance simultaneously.

Term

MDR-TB (Multi-Drug Resistant TB)

Definition

TB caused by Mycobacterium tuberculosis resistant to at least Isoniazid AND Rifampicin (the two most potent first-line drugs). Develops primarily due to inconsistent or incomplete anti-TB treatment. Managed under PMDT using second-line drugs.

Importance

Non-adherence to DOTS causes drug resistance. MDR-TB is a consequence of failed DOTS — a crucial concept for NLE and nursing advocacy.

Section Title

National TB Control Program (NTP) and DOTS

Common Mistakes

  • Thinking DOTS means giving the patient drugs to take at home — DOTS requires the health worker to WATCH the patient swallow each dose.
  • Confusing Category I (new cases) with Category II (previously treated) — know the difference and the drug regimens.
  • Thinking Rifampicin-induced orange-red urine is an adverse reaction requiring drug stoppage — it is NORMAL and expected; reassure the patient.
  • Forgetting that Ethambutol can cause optic neuritis (visual changes) and Streptomycin causes ototoxicity — monitor accordingly.
  • Confusing Isoniazid's side effect (peripheral neuropathy — prevented by Vitamin B6/pyridoxine) with other drug side effects.
  • Thinking BCG prevents all forms of TB — BCG only prevents SEVERE childhood TB (meningitis, miliary TB), not adult pulmonary TB.

Exam Tips

  • IMMEDIATE (24 hours): AFP, Measles, Neonatal Tetanus, Cholera, Meningococcal disease, Rabies.
  • WEEKLY: Dengue, Typhoid, TB, Malaria.
  • AFP = polio until proven otherwise — IMMEDIATE report within 24 hours.
  • NLE question pattern: 'A nurse finds a child with sudden onset of leg weakness — what should the nurse do FIRST?' Answer: Report the case to the health authorities as AFP (within 24 hours).

Key Points

  • The Philippine Integrated Disease Surveillance and Response (PIDSR) system mandates health workers to report certain communicable diseases to public health authorities.
  • IMMEDIATELY NOTIFIABLE (within 24 hours): diseases of epidemic potential and eradication targets — Acute Flaccid Paralysis (AFP/polio), Measles, Neonatal Tetanus, Cholera, Meningococcal disease, Rabies.
  • WEEKLY NOTIFIABLE: routinely reported conditions — Dengue, Typhoid fever, TB, Malaria, Leptospirosis, and others.
  • Prompt and accurate reporting by the nurse triggers immediate investigation, contact tracing, and outbreak response.
  • The community health nurse's role in disease surveillance: detect cases, report immediately, conduct contact tracing, implement control measures, and educate the community.
  • Under RA 9173, nurses have the professional duty to report communicable diseases — failure to do so is negligence.
  • Acute Flaccid Paralysis (AFP): any case of sudden onset of flaccid (floppy) weakness in a child under 15 years — must be reported IMMEDIATELY as a suspected polio case.

Definitions

Term

PIDSR (Philippine Integrated Disease Surveillance and Response)

Definition

The national disease surveillance system of the Philippines, managed by DOH-RESU (Regional Epidemiology Surveillance Units). It mandates healthcare providers to report notifiable diseases within specified timeframes to enable rapid public health response.

Importance

NLE tests which diseases are immediately notifiable vs. weekly notifiable. Know that AFP/polio, measles, cholera, and meningococcal disease are IMMEDIATELY notifiable within 24 hours.

Term

Acute Flaccid Paralysis (AFP)

Definition

A clinical syndrome characterized by sudden onset of weakness or paralysis in one or more limbs, with decreased muscle tone (flaccid), occurring in a child under 15 years of age or in a person of any age with a clinical suspicion of poliomyelitis. Each AFP case must be reported within 24 hours as a potential polio case.

Importance

AFP surveillance is the primary method for detecting poliovirus circulation in the community. Any AFP case = immediate reporting requirement = suspected polio until proven otherwise.

Section Title

Notifiable Diseases and PIDSR

Common Mistakes

  • Reporting dengue as immediately notifiable — dengue is WEEKLY notifiable (unless there is a suspected outbreak).
  • Failing to recognize AFP as an immediate-report case — any sudden flaccid paralysis in a child under 15 = report immediately.
  • Thinking only doctors can report notifiable diseases — nurses under RA 9173 have a legal duty to report.

Exam Tips

  • VECTOR MEMORY: Aedes = Dengue (Day-biting) | Anopheles = Malaria (Night-biting) | Culex = Filariasis/Encephalitis.
  • 4-S Strategy: Search and destroy | Self-protection | Seek early consultation | Support fogging (outbreaks only).
  • Dengue breeds in CLEAN stagnant water — a classic NLE distractor.
  • 4 serotypes = 4 chances to get dengue; 2nd infection with different serotype = more severe.
  • Priority dengue nursing action: monitor for WARNING SIGNS and hydration status.
  • NANDA nursing diagnosis for dengue: Risk for Deficient Fluid Volume; Risk for Bleeding.

Key Points

  • Dengue is a viral disease transmitted by the AEDES AEGYPTI mosquito (also Aedes albopictus), a DAY-BITING mosquito that breeds in CLEAN, STAGNANT WATER (not dirty/stagnant water — this is a common misconception).
  • There are FOUR DENGUE SEROTYPES (DENV 1, 2, 3, 4) — infection with one serotype gives immunity to THAT serotype ONLY.
  • Secondary infection with a DIFFERENT serotype causes more severe dengue (Dengue Hemorrhagic Fever / Dengue Shock Syndrome) due to antibody-dependent enhancement.
  • DOH 4-S STRATEGY: 1) Search and destroy mosquito breeding sites, 2) Self-protection measures, 3) Seek early consultation, 4) Support fogging/spraying only in hotspot areas.
  • FOGGING is NOT the primary control measure — it kills adult mosquitoes but does NOT eliminate breeding sites. Fogging is used only during outbreaks in hotspot areas.
  • DENGUE WARNING SIGNS (refer immediately): severe abdominal pain, persistent vomiting, bleeding (gums, nose, skin), restlessness/altered consciousness, difficulty breathing, rapid pulse.
  • Dengue is NOT directly transmitted from person to person — a mosquito must bite an infected person and then bite another person.
  • Nursing priority for dengue: assess for warning signs, monitor for plasma leakage (bleeding, rapid pulse, drop in blood pressure), ensure adequate hydration.
  • The most common dengue nursing diagnosis: Risk for Deficient Fluid Volume related to plasma leakage and hemorrhage.

Definitions

Term

Aedes aegypti

Definition

The primary mosquito vector of dengue, chikungunya, Zika, and yellow fever. It is a day-biting mosquito (most active 2 hours after sunrise and several hours before sunset) that breeds in clean, stagnant water containers (flower vases, uncovered water drums, discarded tires, etc.).

Importance

NLE frequently tests the vector: Aedes aegypti = dengue. Distinguished from Anopheles (malaria — night-biting) and from the misconception that dengue mosquitoes breed in dirty water.

Term

DOH 4-S Strategy

Definition

The Philippine DOH's four-pronged approach to dengue prevention: (1) Search and destroy mosquito breeding sites — regular cleanup of stagnant water; (2) Self-protection — repellent, long-sleeved clothing, window screens; (3) Seek early consultation — early medical evaluation of fever; (4) Support fogging/spraying — only in outbreak hotspot areas, NOT routine use.

Importance

The 4-S strategy is a guaranteed NLE topic. Know each 'S' and understand why fogging is NOT the first-line measure.

Term

Dengue Hemorrhagic Fever (DHF)

Definition

A severe form of dengue characterized by high fever, hemorrhagic manifestations (bleeding), thrombocytopenia (low platelets), and plasma leakage leading to hemoconcentration. More common in secondary dengue infections due to antibody-dependent enhancement.

Importance

DHF represents secondary prevention failure — the nurse must detect warning signs early. Priority nursing intervention: fluid replacement and bleeding precautions.

Section Title

Dengue Control and the DOH 4-S Strategy

Common Mistakes

  • Saying Aedes aegypti breeds in DIRTY stagnant water — Aedes breeds in CLEAN stagnant water (vases, drums, containers).
  • Recommending fogging as the PRIMARY dengue control measure — fogging is supplementary, used only in outbreak hotspots.
  • Confusing Aedes aegypti (dengue, day-biting) with Anopheles (malaria, night-biting).
  • Thinking all dengue serotype infections give cross-immunity — each serotype gives immunity to THAT serotype ONLY; second infection with a different serotype = more severe disease.
  • Forgetting that dengue is a NOTIFIABLE disease (weekly reporting to PIDSR).

Exam Tips

  • Schistosomiasis in Philippines = Schistosoma japonicum + Oncomelania snail + freshwater exposure.
  • Malaria = Anopheles (night); Dengue = Aedes (day); Filariasis = Culex.
  • Rabies PEP Category III = vaccine + IMMUNOGLOBULIN (both needed).
  • Leprosy MDT: Dapsone + Rifampicin + Clofazimine.
  • RA 9482 = Anti-Rabies Act; RA 10152 = Mandatory Immunization Act; RA 9173 = Philippine Nursing Act.

Key Points

  • MALARIA: transmitted by the ANOPHELES mosquito (night-biting). Endemic in parts of Palawan, Mindanao, and other provinces. Control: Long-Lasting Insecticidal Nets (LLINs), indoor residual spraying, case management with antimalarials.
  • SCHISTOSOMIASIS: caused by Schistosoma japonicum (blood fluke). Intermediate host: ONCOMELANIA snail (freshwater snail). Endemic in parts of Leyte, Samar, Mindanao, and Sorsogon. Transmission through skin contact with infested freshwater.
  • FILARIASIS: caused by Wuchereria bancrofti, transmitted by Culex mosquito. Causes lymphedema (elephantiasis). DOH has a national elimination program (Mass Drug Administration with DEC and Albendazole).
  • LEPROSY (Hansen's Disease): caused by Mycobacterium leprae. DOH aims for elimination. Treatment: Multi-Drug Therapy (MDT) — Dapsone, Rifampicin, Clofazimine. Primary mode of transmission: prolonged close contact (droplet/nasal secretions).
  • RABIES: caused by Rabies virus, transmitted through bites/scratches from infected animals (dogs most common in the Philippines). Post-exposure prophylaxis (PEP): wound wash, anti-rabies vaccine series, and anti-rabies immunoglobulin for Category III exposures. The Philippines has the Rabies Prevention and Control Act (RA 9482).
  • The ONCOMELANIA snail is the specific intermediate host for Philippine schistosomiasis — NOT the Biomphalaria snail (which is for African schistosomiasis).

Definitions

Term

Schistosomiasis (Philippine Bilharzia)

Definition

A parasitic infection caused by Schistosoma japonicum in the Philippines. Cercariae (larval forms) penetrate the skin during contact with infested freshwater containing infected Oncomelania snails. Causes liver enlargement, intestinal manifestations, and anemia. Treated with Praziquantel.

Importance

NLE tests the causative organism (Schistosoma japonicum), intermediate host (Oncomelania snail), and endemic areas. Key distinction: Philippine schistosomiasis = japonicum (NOT mansoni or haematobium).

Term

RA 9482 (Anti-Rabies Act of 2007)

Definition

Philippine law mandating rabies prevention and control measures, including mandatory registration and vaccination of dogs, establishment of animal bite treatment centers, and provision of free post-exposure prophylaxis for indigent patients.

Importance

Know the law number for NLE. Post-exposure prophylaxis categories: Category I (no exposure — no PEP), Category II (minor scratches — vaccine only), Category III (bites/licks on mucosa — vaccine + immunoglobulin).

Section Title

Other Endemic Diseases in the Philippine Context

Common Mistakes

  • Saying the intermediate host of Philippine schistosomiasis is Biomphalaria — the Philippines uses ONCOMELANIA snail; Biomphalaria is for S. mansoni in Africa.
  • Confusing Anopheles (malaria) with Culex (filariasis) mosquitoes.
  • Giving anti-rabies immunoglobulin for Category II exposure — immunoglobulin is ONLY for Category III (deep bites, bites on face/neck, multiple bites).
  • Saying leprosy is highly contagious — leprosy has LOW infectivity; prolonged close contact is required.

Connections

  • Levels of Prevention connect to ALL community health programs: EPI = Primary Prevention (specific protection); DOTS case detection = Secondary Prevention; TB rehabilitation = Tertiary Prevention.
  • Immunity types connect to EPI vaccines: BCG, Pentavalent, OPV, PCV, MMR, and IPV all produce ARTIFICIAL ACTIVE immunity — contrast with immunoglobulins which provide passive immunity.
  • Cold chain connects to vaccine efficacy: if the cold chain fails (OPV exposed to heat, or DPT frozen), the vaccine may be ineffective, resulting in unprotected children — this directly affects FIC/CIC coverage indicators.
  • Tetanus (Td) immunization for women connects to neonatal tetanus elimination — maternal Td2 = passive transfer of antibodies to newborn = CPAB indicator — links to MCH nursing and newborn care.
  • DOTS and direct observation connect to medication adherence principles seen in all chronic disease management (e.g., anti-retroviral therapy for HIV, MDT for leprosy) — the principle of supervised treatment to prevent resistance.
  • Dengue control (4-S, Aedes aegypti, clean stagnant water) connects to environmental health nursing — emphasizing vector control as a community-level nursing intervention.
  • Notifiable disease reporting under PIDSR connects to RA 9173 — the Philippine Nursing Act mandates professional accountability, including timely disease reporting as a legal and ethical duty.
  • EPI vaccines and their routes connect to drug administration competencies: BCG (ID), OPV (oral), MMR (SC), Pentavalent/PCV/IPV/HepB (IM) — skills tested in both NLE and clinical practice.
  • TB DOTS connects to social determinants of health — poverty, overcrowding, malnutrition, and inadequate ventilation are risk factors; the community nurse addresses these through health education and referral.
  • Drug-resistant TB (MDR-TB) connects to the public health consequence of inadequate DOTS implementation — emphasizing the importance of directly observed therapy to prevent resistance.

Exam Strategy

For NLE success in this chapter, organize your review around three priority clusters: (1) EPI SCHEDULE & VACCINES — know the exact ages/weeks, routes, doses, and sites for every vaccine by heart; create a table and drill it daily. (2) COLD CHAIN & FEFO — memorize heat-sensitive (OPV > Measles > BCG) vs. freeze-sensitive vaccines (DPT, Hep B, Td, Pentavalent) and the shake test. (3) DOTS & TB TREATMENT — internalize the 5 elements of DOTS, the drug abbreviations (HRZE-S), Category I (2HRZE/4HR), and all drug side effects. For item analysis: NLE questions often use clinical scenarios — a child presenting with a particular disease history, a nurse finding a cold chain problem, or a mother asking about vaccination. Always apply the NURSING PROCESS: Assess the situation, identify the correct nursing diagnosis or action, and implement based on DOH program guidelines. For priority-type NLE questions: use Maslow's hierarchy — physiologic safety (airway, circulation) first, then psychological needs. In communicable disease, warning signs (dengue bleeding, TB drug toxicity) always take priority. Remember key laws: RA 9173 (Nursing Act), RA 10152 (Mandatory Immunization), PD 996 (compulsory immunization), RA 9482 (Anti-Rabies). On exam day: for any EPI question, immediately recall your mental vaccine schedule table. For any TB question, recall the DOTS 5 elements and drug acronym HRZE-S. For dengue, recall 4-S and Aedes aegypti (clean water, day-biting).

Quick Review Questions

A community health nurse is conducting a health teaching session on vaccine-preventable diseases. A mother asks what type of immunity her baby gets from the BCG vaccine. What is the CORRECT response?

Vaccines, including BCG, stimulate the individual's own immune system to produce antibodies and memory cells — this is ARTIFICIAL ACTIVE immunity. It is 'artificial' because it comes from a vaccine (not natural infection), and 'active' because the baby's own immune system is doing the work. This is long-lasting. Do not confuse with passive immunity (from immunoglobulins or from the mother via placenta/breast milk).

According to the current DOH EPI schedule, which THREE vaccines are given simultaneously at 6 weeks, 10 weeks, and 14 weeks of age?

All three vaccines follow the 6-10-14 week schedule with 3 doses each. The minimum interval between doses in the series is 4 weeks (28 days). The IPV (inactivated polio) is given at 14 weeks and 9 months — a different schedule from OPV. This is a classic NLE question testing the EPI schedule.

The nurse is preparing to administer BCG vaccine to a newborn at the birthing center. What is the CORRECT route, site, and dose for BCG administration?

BCG is ALWAYS given intradermally (ID), not IM or SC. The dose for infants is 0.05 mL (0.1 mL is used for older children). The site is the right upper arm/deltoid region. A successful BCG take produces a wheal at the injection site, which later forms a small scar. Giving BCG SC or IM may cause abscess formation.

A nurse is checking the cold chain at the rural health unit. She notices the freeze-sensitive vaccines (Pentavalent, Hepatitis B, Td) have been stored in the freezer section by mistake. What is the nurse's priority action?

Freeze-sensitive vaccines (DPT, Hepatitis B, Td, Pentavalent) must NEVER be frozen — freezing destroys their potency by causing irreversible adsorption damage. The shake test is the standard field method: shake the vial and compare with a known good (unfrozen) control — if a precipitate forms and does NOT redissolve, the vaccine is damaged and must be discarded. The nurse must not administer potentially damaged vaccines.

A pregnant woman comes to the health center for her first prenatal visit at 6 months gestation. This is her first pregnancy and she has no prior record of Td immunization. The nurse gives her Td1 today. When should Td2 be given, and what does Td2 protect against?

The minimum interval between Td1 and Td2 is 4 weeks. Td2 is the critical dose that enables the mother to transfer maternal antibodies to the newborn, protecting against neonatal tetanus. This makes the newborn a 'Child Protected at Birth (CPAB).' Remember: Td1 gives NO protection — protection begins with Td2. Td2 should be given at least 2-3 weeks before the expected delivery date.

What is the PRIMARY diagnostic test for tuberculosis under the current Philippine National TB Program (NTP)?

The current NTP has shifted to GeneXpert as the initial diagnostic tool because of its speed, sensitivity, and ability to detect drug resistance (rifampicin resistance indicates likely MDR-TB). Direct Sputum Smear Microscopy (DSSM) is now used primarily for treatment monitoring and follow-up, not initial diagnosis. This is a current-update NLE point — some older review materials still list DSSM as the primary test.

A patient with newly diagnosed pulmonary TB (new smear-positive case) is started on Category I treatment. What does the regimen '2HRZE/4HR' mean?

Category I is for new TB cases. The mnemonic HRZE stands for: H=Isoniazid, R=Rifampicin, Z=Pyrazinamide, E=Ethambutol. The intensive phase uses all 4 drugs for 2 months to rapidly reduce the bacillary load. The continuation phase uses only 2 drugs (HR) for 4 months to eliminate remaining bacteria. Category II (previously treated cases) uses a longer regimen that includes Streptomycin (S).

A patient on anti-TB medication calls the health center and reports that his urine has turned orange-red. He is worried. What is the CORRECT nursing response?

Rifampicin (R) causes discoloration of body fluids — urine, sweat, tears, and saliva turn orange-red or rust-colored. This is NORMAL and expected. It is not a sign of bleeding or organ damage. Patients should be educated about this before starting treatment so they are not alarmed. If the nurse advises stopping medication unnecessarily, this can lead to drug resistance and treatment failure.

During a community health assessment, a nurse identifies a 7-year-old child with sudden onset of flaccid weakness in both lower extremities, beginning 3 days after a febrile illness. What disease should the nurse suspect, and what is the reporting requirement under PIDSR?

Any case of Acute Flaccid Paralysis (AFP) in a child under 15 years must be reported within 24 hours as a suspected polio case. AFP surveillance is the primary means of detecting poliovirus circulation. Under RA 9173, the community nurse has a professional duty to report. The case will trigger investigation, stool specimen collection for poliovirus isolation, and contact tracing/immunization response.

Which of the following best describes the DOH 4-S strategy for dengue prevention, and what is the MOST effective primary measure?

Dengue is caused by Aedes aegypti, which breeds in CLEAN STAGNANT WATER. The most effective way to control dengue is to eliminate breeding sites (searching and destroying containers with stagnant water). Fogging kills adult mosquitoes but does not address breeding sites and is recommended ONLY during outbreaks in hotspot areas — it is NOT a routine measure. Self-protection (repellent, clothing) and early consultation for fever are also important.

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