PhLE Pharmacology and Pharmacotherapeutics Review
PhLE Pharmacology and Pharmacotherapeutics Review
PhLE Pharmacology + Pharmacotherapeutics is the heaviest content subject. Memorisation-intensive but high-leverage.
What PRC asks
| Topic block | Approx. items |
|---|---|
| Cardiovascular drugs | 12 |
| Respiratory drugs | 8 |
| GI drugs | 8 |
| Endocrine drugs (especially diabetes, thyroid) | 10 |
| Antimicrobials (antibiotics, antivirals, antifungals) | 15 |
| Anti-inflammatories + analgesics | 10 |
| CNS drugs (psych, neuro) | 12 |
| Antineoplastics | 8 |
| Hematology drugs | 5 |
| Pharmacokinetics + drug interactions | 8 |
| Toxicology | 4 |
Cardiovascular
- ACE inhibitors, ARBs
- Beta-blockers
- Calcium channel blockers
- Diuretics (loop, thiazide, K-sparing)
- Digoxin (toxicity!)
- Antianginals
- Antiarrhythmics
- Antihyperlipidemics (statins, fibrates)
Respiratory
- Bronchodilators (beta-2 agonists, anticholinergics)
- Inhaled corticosteroids
- Leukotriene modifiers
- Theophylline (narrow therapeutic index)
GI
- Antacids, H2 blockers, PPIs
- Antiemetics
- Anti-diarrheals
- Laxatives
- IBD drugs (5-ASA, biologics)
Endocrine
- Insulins (rapid, short, intermediate, long-acting)
- Oral antidiabetics (metformin, sulfonylureas, DPP-4, SGLT-2, GLP-1)
- Thyroid: levothyroxine, methimazole, PTU
- Corticosteroids
- Sex hormones
Antimicrobials
- Penicillins (natural, antistaph, antipseudomonal)
- Cephalosporins (1st-5th generation)
- Macrolides
- Tetracyclines, doxycycline
- Aminoglycosides (toxicity: nephro/oto)
- Fluoroquinolones
- Sulfonamides
- Antitubercular (RIPE)
- Antifungals (azoles, polyenes)
- Antivirals (anti-HIV, anti-HSV, anti-influenza)
Anti-inflammatories + analgesics
- NSAIDs
- Opioids
- Acetaminophen
- DMARDs
CNS
- Antipsychotics (typical vs atypical, EPS, NMS)
- Antidepressants (SSRIs, SNRIs, tricyclics, MAOIs)
- Mood stabilisers (lithium, valproate)
- Anxiolytics (benzodiazepines, buspirone)
- Anticonvulsants
- Antiparkinsonian (levodopa, dopamine agonists)
- Sedative-hypnotics
Antineoplastics
- Alkylating agents
- Antimetabolites
- Plant alkaloids
- Hormonal therapies
- Biologics
Pharmacokinetics
- ADME (absorption, distribution, metabolism, elimination)
- Half-life calculations
- Loading + maintenance dose
- Therapeutic drug monitoring
A 5-week drilling plan
| Week | Focus | Volume target |
|---|---|---|
| 1 | Cardiovascular + Respiratory + GI | 100 items |
| 2 | Endocrine + Antimicrobials | 100 items |
| 3 | Anti-inflammatories + CNS | 100 items |
| 4 | Antineoplastics + Hematology + Pharmacokinetics | 70 items |
| 5 | Mixed mock + remediation | 1 mock + 60 items |
Realistic scores
| Diagnostic baseline | Realistic test-day score |
|---|---|
| 55% | 75% |
| 65% | 82% |
| 75% | 87% |
Where Super Tutor fits
Super Tutor's PhLE track covers Pharmacology.
What to read next
The PhLE 2026 pillar guide covers the full review.
Start your PHLE-PHARMACY review
Super Tutor covers PHLE-PHARMACY with an AI review plan tuned to your weak areas.
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