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NLE Perioperative & Pain NursingPain ManagementCheat Sheet

A printable cheat sheet for Pain Management, built for NLE reviewers who want one go-to reference in the final stretch. Covers formulas, key definitions, common question types, and the Professional Regulation Commission (PRC) — Board of Nursing-specific twists you will see on NLE day.

Exam context

For the Philippine Nurse Licensure Examination (PNLE), Professional Regulation Commission (PRC) — Board of Nursing tests Perioperative & Pain Nursing under a "Core" label, with Pain Management in the 3rd slot across 3 chapters. NLE candidates must clear the 75% weighted average with no sub-test below 60% cut on the 2026 paper, which draws about 50 Perioperative & Pain Nursing questions. Date to watch: Bi-annual.

Pain Management - Cheat Sheet

Your last-minute revision companion for Pain Management in Perioperative & Pain Nursing. This rapid-fire reference covers pain physiology, assessment tools, pharmacologic and non-pharmacologic management, critical safety rules, and high-yield NLE facts.

Sections

Section Title

Pain Physiology & Definition

Important Facts

  • Transduction: noxious stimulus activates nociceptors → nerve impulse generated.
  • Transmission: impulse travels peripheral nerve → spinal cord → brain.
  • Perception: brain becomes conscious of pain.
  • Modulation: body dampens or amplifies signal via endogenous opioids (endorphins) and descending pathways.
  • Gate Control Theory: non-painful stimuli (rubbing, heat, massage) 'close the gate' in spinal cord and reduce pain transmission—rationale for non-drug measures.
  • Pain is subjective; objective signs may be absent in chronic pain.

Key Definitions

Term

Pain (Gold Standard Definition)

Example

A patient reports 7/10 pain even if no objective signs are visible; this IS pain and must be treated.

Definition

Whatever the patient says it is, existing whenever the patient says it does—the patient's self-report is the MOST RELIABLE indicator.

Term

Acute Pain

Example

Post-operative pain, acute fracture, appendicitis.

Definition

Recent onset, protective warning of tissue injury, resolves as healing occurs (under 3–6 months); accompanied by sympathetic responses (tachycardia, hypertension, diaphoresis).

Term

Chronic (Persistent) Pain

Example

Diabetic neuropathy, chronic back pain, cancer pain.

Definition

Lasts beyond expected healing (longer than 3–6 months); may lack outward physiologic signs; associated with fatigue, depression, functional limitation.

Term

Nociceptive Pain

Example

Post-surgical pain (somatic), post-MI pain (visceral).

Definition

From actual tissue damage; includes somatic (well localized, aching/throbbing) and visceral (deep, cramping, poorly localized, may be referred).

Term

Neuropathic Pain

Example

Diabetic neuropathy, phantom limb pain, shingles.

Definition

From nerve damage or dysfunction; described as burning, shooting, tingling, electric-like.

Diagrams To Know

  • The four processes of nociceptive pain transmission (transduction → transmission → perception → modulation).
  • Gate Control Theory mechanism in the spinal cord.

Common Values

Value

30–60 minutes

Symbol

N/A

Quantity

Reassessment timing after oral analgesia

Value

15–30 minutes

Symbol

N/A

Quantity

Reassessment timing after IV analgesia

Value

0–10

Symbol

N/A

Quantity

FLACC total score range

Section Title

Pain Assessment Tools & PQRST

Important Facts

  • Always REASSESS pain after intervention: 30–60 minutes post oral analgesia, 15–30 minutes post IV.
  • Assessment includes effect on function, sleep, mood, and cultural factors.
  • Patient's self-report is ALWAYS the gold standard—do not rely on objective signs alone.
  • Use age-appropriate and condition-appropriate tools (nonverbal, pediatric, elderly).
  • Document baseline pain, location, quality, severity, and response to treatment.

Key Definitions

Term

PQRST Mnemonic

Example

Patient states sharp pain in right lower quadrant, worse with movement, better with rest, began acutely 2 hours ago—classic appendicitis presentation.

Definition

Systematic pain assessment framework: Provocation/Palliation (what makes it better/worse), Quality (sharp/dull/burning/cramping), Region/Radiation, Severity (intensity on scale), Timing (onset/duration/pattern).

Term

Numeric Rating Scale (NRS)

Example

Patient reports 7/10 pain.

Definition

0–10 scale where 0 = no pain, 10 = worst imaginable pain; standard for adults and older children.

Term

Wong-Baker FACES Scale

Example

Child points to crying face = moderate to severe pain.

Definition

Cartoon faces from smiling to crying; useful for young children (~3 years+) and patients with communication barriers.

Term

FLACC Scale

Example

Tight face (2) + rigid legs (2) + no activity (2) + high cry (2) + difficult to console (2) = 10/10.

Definition

Behavioral tool for infants and nonverbal patients: scoring Face, Legs, Activity, Cry, Consolability (each 0–2, total 0–10) by observation.

Diagrams To Know

  • PQRST framework for systematic pain history.
  • Pain rating scales in visual format (0–10, faces, FLACC scoring).

Common Values

Value

~4 g/day (less with liver disease)

Symbol

N/A

Quantity

Acetaminophen max daily dose

Value

5 days

Symbol

N/A

Quantity

Ketorolac max duration

Section Title

WHO Analgesic Ladder & Non-Opioid Analgesics

Important Facts

  • WHO Ladder: use NON-OPIOIDS first (Step 1) before escalating.
  • Dose analgesics AROUND THE CLOCK for continuous pain, not only 'as needed'.
  • Acetaminophen MAX ~4 g/day (less with liver disease or alcohol use); hepatotoxicity is silent and dangerous.
  • NSAIDs: give WITH FOOD, watch for black tarry stools (GI bleeding), monitor renal function, use caution in older adults and those with peptic ulcer disease.
  • Adjuvant drugs (antidepressants, anticonvulsants like gabapentin/pregabalin, corticosteroids) especially useful for neuropathic pain.
  • Ketorolac (Toradol) is short-acting ONLY (max 5 days)—high risk of GI and renal toxicity.
  • Oral route preferred when patient can tolerate.

Key Definitions

Term

WHO Analgesic Ladder

Example

Start acetaminophen for post-operative pain; if inadequate, add codeine; if still inadequate, switch to morphine.

Definition

Three-step approach for pain management, especially cancer and chronic pain: Step 1 (mild) non-opioids → Step 2 (mild–moderate) weak opioids added → Step 3 (moderate–severe) strong opioids added; adjuvants at any step.

Term

Acetaminophen (Paracetamol)

Example

Max dose ~4 g/day in adults; overdose antidote is acetylcysteine.

Definition

Non-opioid analgesic and antipyretic with MINIMAL anti-inflammatory effect; DANGER IS HEPATOTOXICITY.

Term

NSAIDs (Ibuprofen, Naproxen, Ketorolac)

Example

Give with food to reduce GI upset; ketorolac for short-term only (risk of GI/renal damage).

Definition

Non-opioid analgesics that reduce pain, fever, inflammation by inhibiting prostaglandins; WATCH FOR GI BLEEDING, RENAL IMPAIRMENT, INCREASED BLEEDING.

Diagrams To Know

  • WHO Analgesic Ladder step-by-step progression.
  • Acetaminophen vs NSAID comparison and adverse effects.

Common Values

Value

< 12 breaths/min (institutional policy may vary)

Symbol

RR

Quantity

Respiratory rate threshold for holding opioid

Value

2–10 mg every 3–4 hours

Symbol

N/A

Quantity

Morphine typical IV dose

Value

10–30 mg every 3–4 hours

Symbol

N/A

Quantity

Morphine typical oral dose

Section Title

Opioid Analgesics - CRITICAL SAFETY

Important Facts

  • RESPIRATORY DEPRESSION IS THE #1 OPIOID DANGER—assess RR BEFORE giving opioid.
  • HOLD OPIOID DOSE AND NOTIFY PROVIDER IF RR < 12 (or per institutional policy); watch for increasing sedation which precedes respiratory depression.
  • Monitor level of consciousness, oxygen saturation, and blood pressure.
  • NALOXONE is the opioid antidote—short-acting; repeat dosing or infusion may be needed; can precipitate acute withdrawal and pain return.
  • CONSTIPATION DOES NOT RESOLVE WITH TOLERANCE—treat proactively with stimulant laxative, fluids, fiber, activity.
  • Adverse effects: respiratory depression, sedation, constipation, nausea/vomiting, urinary retention, hypotension, pruritus, miosis (pinpoint pupils).
  • Use caution in older adults (more sensitive, slower clearance), respiratory disease, hepatic/renal impairment, opioid-naive patients.
  • Patients with substance use disorder still deserve adequate pain relief; treat pain with clear monitoring plan.
  • Tolerance, physical dependence, and addiction are DISTINCT—do NOT undertreat pain due to unfounded addiction fears.
  • In cancer and palliative care, opioids are given generously; NO arbitrary ceiling on titration for severe pain.

Key Definitions

Term

Opioid Analgesics (Morphine, Fentanyl, Hydromorphone, Oxycodone, Codeine, Tramadol)

Example

Morphine: typical dose 2–10 mg IV or 10–30 mg orally every 3–4 hours, titrated to effect and per order.

Definition

Bind opioid receptors to relieve moderate to severe pain; MOST DANGEROUS RISK IS RESPIRATORY DEPRESSION.

Term

Naloxone (Antidote/Reversal Agent)

Example

Give naloxone if RR < 8 or severe sedation; monitor for return of pain and acute withdrawal.

Definition

OPIOID ANTAGONIST that reverses respiratory depression and sedation in opioid overdose; short-acting (repeat dosing or infusion may be needed).

Term

Tolerance

Example

Patient on long-term morphine may need dose escalation over time.

Definition

Need for increasing doses to achieve same analgesic effect; NOT the same as addiction.

Term

Physical Dependence

Example

Sweating, anxiety, muscle aches if opioid is suddenly stopped.

Definition

Body's physiologic adaptation to opioid; withdrawal occurs on abrupt cessation; NOT the same as addiction.

Term

Addiction

Example

Patient seeks opioids for euphoria, not pain relief; lies about doses.

Definition

Compulsive use despite harm, loss of control, continued use despite negative consequences; TRUE psychological disorder.

Diagrams To Know

  • Opioid safety checklist: RR assessment → dose decision → monitoring parameters → naloxone availability.
  • Tolerance vs Physical Dependence vs Addiction comparison.

Common Values

Value

5–10 minutes

Symbol

N/A

Quantity

Typical PCA lockout interval

Section Title

Patient-Controlled Analgesia (PCA)

Important Facts

  • ONLY THE PATIENT should press the PCA button—NO family members, NO PCA by proxy.
  • Teach patient to press button WHEN PAIN BEGINS, not waiting until pain is severe.
  • Verify drug, concentration, dose, lockout interval, and limits with SECOND NURSE before use.
  • Monitor respiratory rate, sedation level, oxygen saturation, pain relief; document amounts delivered and attempted.
  • Ensure NALOXONE and resuscitation equipment are IMMEDIATELY AVAILABLE.
  • Most common opioid for PCA: morphine.
  • PCA works best for acute post-operative pain and acute exacerbations of chronic pain.
  • If patient is sedated or respiratory depression develops, hold further dosing, check RR, consider naloxone.

Key Definitions

Term

PCA (Patient-Controlled Analgesia)

Example

Post-operative patient presses PCA button when pain begins; gets small IV morphine dose immediately.

Definition

Allows patient to self-administer preset IV opioid dose by pressing button; provides steady pain control and patient autonomy.

Term

Lockout Interval

Example

Common lockout = 5–10 minutes; patient cannot receive another dose within this window even if button is pressed repeatedly.

Definition

Time period after each dose during which the PCA will not deliver another dose; prevents overdose.

Term

PCA by Proxy

Example

Family member presses button to help patient → patient receives opioid doses patient didn't request → respiratory depression risk.

Definition

UNSAFE PRACTICE where family member or staff member presses the button for the patient; HIGH OVERDOSE RISK.

Diagrams To Know

  • PCA setup and operation flowchart.
  • Lockout interval timeline.

Section Title

Non-Pharmacologic Pain Management

Important Facts

  • Non-pharmacologic measures COMPLEMENT medications—not replace them.
  • Especially valuable for CHRONIC PAIN and to REDUCE OPIOID REQUIREMENTS.
  • Cutaneous stimulation: heat (muscle tension, arthritis), cold (acute injury, inflammation), massage, TENS unit.
  • Cognitive-behavioral: relaxation and breathing techniques, guided imagery, distraction (music, TV, conversation), biofeedback.
  • Positioning, rest, and immobilization of painful part reduce pain.
  • Acupuncture and acupressure supported by some evidence.
  • Support functional goals: improved sleep, activity, quality of life (especially chronic pain).
  • Multimodal approach (combining pharmacologic and non-pharmacologic) is most effective.

Key Definitions

Term

Gate Control Theory Application

Example

Rubbing a child's bumped knee → non-painful sensory input closes gate → child feels less pain.

Definition

Non-painful stimuli (rubbing, heat, massage) 'close the gate' in spinal cord and reduce pain transmission; rationale for non-drug measures.

Term

Cutaneous Stimulation

Example

Warm compress for muscle tension, ice pack for acute injury, TENS unit for chronic neuropathic pain.

Definition

Physical therapies: heat, cold, massage, TENS (transcutaneous electrical nerve stimulation).

Term

Cognitive-Behavioral Strategies

Example

Guided visualization of peaceful place, listening to music, deep breathing exercises.

Definition

Mental techniques: relaxation, guided imagery, distraction, music, biofeedback.

Diagrams To Know

  • Gate Control Theory mechanism.
  • Non-pharmacologic interventions categorized by type (cutaneous, cognitive-behavioral, positional).

Common Values

Value

5–10 minutes

Symbol

N/A

Quantity

IV opioid onset time

Section Title

Routes of Administration & Special Populations

Important Facts

  • ORAL ROUTE PREFERRED when patient can tolerate (cost-effective, patient preference).
  • IV: fastest onset (~5–10 min), ideal for acute severe pain (post-operative, trauma).
  • Transdermal (fentanyl patch): for STABLE chronic pain ONLY—NOT for acute or opioid-naive patients (risk of overdose).
  • OLDER ADULTS: more sensitive to opioids/sedation, slower drug clearance, prone to NSAID-related GI and renal harm. START LOW AND GO SLOW; reassess frequently.
  • OPIOID-NAIVE patients: EXTRA MONITORING for respiratory depression required.
  • PEDIATRIC: dose by weight, use age-appropriate assessment tools (FLACC for infants/toddlers, Wong-Baker for young children, NRS 0–10 for older children).
  • SUBSTANCE USE DISORDER history: still deserve adequate pain relief; establish CLEAR TREATMENT PLAN and CLOSE MONITORING.
  • Use equianalgesic dosing charts when switching routes/drugs.

Key Definitions

Term

Equianalgesic Dosing

Example

Using equianalgesic chart when switching from oral morphine to fentanyl patch.

Definition

Converting between different opioid routes or drugs while maintaining same analgesic effect; prevents under- or over-dosing.

Term

Routes of Analgesic Administration

Example

Oral for chronic pain, IV for post-operative acute pain, transdermal fentanyl patch for stable cancer pain.

Definition

Oral (preferred when tolerated), IV (fastest onset for acute severe pain), transdermal (stable chronic pain), subcutaneous, rectal, epidural, intrathecal.

Diagrams To Know

  • Routes of analgesic administration and onset times.
  • Equianalgesic dosing principles.

Common Values

Value

> 3–6 months

Symbol

N/A

Quantity

Chronic pain duration threshold

Section Title

Chronic Pain Management & Interdisciplinary Approach

Important Facts

  • Chronic pain (>3–6 months) requires MULTIMODAL, INTERDISCIPLINARY approach—no single treatment is adequate.
  • Set FUNCTIONAL GOALS, not pain elimination (often unrealistic).
  • Address depression, anxiety, social isolation that accompany chronic pain.
  • BELIEVE THE PATIENT'S REPORT—do NOT undertreat pain due to addiction fears.
  • Adjuvant drugs crucial: antidepressants (amitriptyline, duloxetine), anticonvulsants (gabapentin, pregabalin), corticosteroids for neuropathic pain.
  • Around-the-clock long-acting opioids + short-acting breakthrough doses in cancer pain.
  • Monitor for tolerance (need more for same effect), physical dependence (withdrawal on abrupt stop), and addiction (distinct from tolerance/dependence).
  • In cancer and palliative care: opioids given generously to relieve suffering—NO arbitrary ceiling on titration for severe pain.
  • Coordination between specialists: pain management physician, nurse, physical therapist, psychologist, social worker.

Key Definitions

Term

Chronic Pain Management

Example

Chronic back pain patient: long-acting morphine + short-acting breakthrough dose + gabapentin + physical therapy + cognitive-behavioral therapy.

Definition

Multimodal, interdisciplinary approach combining analgesics (often around-the-clock long-acting with breakthrough doses), adjuvants, physical therapy, and psychological support.

Term

Functional Goals

Example

Goal: patient can sleep 6 hours without interruption, walk 30 minutes daily, return to work part-time.

Definition

Patient-centered outcomes in chronic pain: improved sleep, activity, work, social participation, and QUALITY OF LIFE—NOT total pain elimination.

Diagrams To Know

  • Chronic pain management multidisciplinary team and approach.
  • Tolerance vs Physical Dependence vs Addiction clarification.

Section Title

Nursing Diagnoses & NLE High-Yield Content

Important Facts

  • Pain assessment is FOUNDATION of all pain management nursing diagnoses.
  • ALWAYS ask patient about pain—do not assume absence of complaints means no pain.
  • Document pain using PQRST; rate severity on standardized scale; reassess after intervention.
  • Nursing interventions span pharmacologic (administer analgesics per order, monitor response, watch for adverse effects) and non-pharmacologic (positioning, comfort measures, distraction, relaxation).
  • Patient education: how to use PCA, realistic pain goals, importance of around-the-clock dosing for chronic pain.
  • Advocacy: ensure patient receives adequate pain relief; challenge myths about opioids and addiction.
  • Cultural sensitivity: pain expression varies by culture; respect patient's pain management preferences.
  • Coordinate with interdisciplinary team: physician, pharmacist, physical therapist, psychologist for optimal pain management.

Key Definitions

Term

NANDA-I Nursing Diagnosis: Acute Pain

Example

Acute Pain r/t post-operative incision AEB 8/10 on pain scale, tachycardia, guarding behavior.

Definition

Unpleasant sensory and emotional experience arising from actual or potential tissue damage, lasting less than 3 months; related to post-operative trauma, injury, inflammation.

Term

NANDA-I Nursing Diagnosis: Chronic Pain

Example

Chronic Pain r/t diabetic neuropathy AEB report of burning sensation in feet, depression, sleep disruption, fatigue.

Definition

Pain lasting more than 3 months, may not have visible objective signs; related to chronic disease, cancer, neuropathy; impacts function and mood.

Diagrams To Know

  • Nursing process applied to pain management (assessment → diagnosis → planning → intervention → evaluation).
  • Maslow hierarchy and pain (physiologic need; safety need for absence of suffering).

Must Remember

  • Pain is WHATEVER THE PATIENT SAYS IT IS, existing whenever the patient says it does—ALWAYS believe patient's self-report; objective signs may be absent, especially in chronic pain.
  • ASSESS RESPIRATORY RATE BEFORE GIVING OPIOID; HOLD DOSE AND NOTIFY PROVIDER IF RR < 12 (or per institutional policy)—respiratory depression is the #1 opioid danger.
  • NALOXONE (opioid antidote) is SHORT-ACTING; repeat dosing or IV infusion may be needed because naloxone wears off before the opioid does; have resuscitation equipment ready.
  • CONSTIPATION DOES NOT RESOLVE WITH TOLERANCE—proactively prescribe stimulant laxative, fluids, fiber, and activity with all opioid regimens.
  • ACETAMINOPHEN HEPATOTOXICITY is the #1 danger—max dose ~4 g/day in adults (less with liver disease/alcohol); antidote is acetylcysteine.
  • NSAIDs CAUSE GI BLEEDING and RENAL IMPAIRMENT—give WITH FOOD; watch for black tarry stools; ketorolac short-term ONLY (max 5 days).
  • ONLY THE PATIENT presses the PCA button—NO family members, NO 'PCA by proxy' (extreme overdose risk); verify drug/dose/lockout interval with second nurse.
  • WHO LADDER (mild → moderate → severe) uses AROUND-THE-CLOCK DOSING for continuous pain, NOT as-needed; add adjuvants for neuropathic pain.
  • TOLERANCE, PHYSICAL DEPENDENCE, and ADDICTION are DISTINCT—tolerance and dependence do NOT indicate addiction; do NOT undertreat pain due to addiction fears.
  • REASSESS PAIN after intervention: 30–60 minutes after oral analgesia, 15–30 minutes after IV—document baseline pain, intervention, and response using PQRST and standardized scale.

Last Minute Tips

  • If NLE question mentions 'patient says pain is 7/10 but has no vital sign changes'—THAT IS VALID PAIN. Believe the patient. Objective signs may be absent in chronic pain.
  • For opioid questions: ALWAYS think 'respiratory depression first.' If respiratory rate is borderline (RR 12–14), reassess sedation level and consider holding dose pending provider evaluation.
  • PCA by Proxy = WRONG AND DANGEROUS. Only patient presses button. Lockout interval prevents overdose. If patient is too sedated to press button, PCA is not appropriate.
  • Acetaminophen toxicity is cumulative and SILENT (patient may have liver damage without symptoms). Remember ~4 g/day max and watch for products containing acetaminophen (many OTC combos).
  • On chronic pain questions, remember the interdisciplinary team (MD, RN, PT, psychologist) and FUNCTIONAL GOALS (sleep, activity, QOL)—not total pain elimination. Address depression and anxiety.

Comparison Tables

Rows

Values

  • Adults, older children
  • Self-report
  • 0–10
  • Standard, quick, universally understood

Property

Numeric Rating Scale (NRS)

Values

  • Young children (~3 yrs+), communication barriers
  • Point to cartoon faces
  • 0–10 (faces)
  • Visual, non-verbal, culturally universal

Property

Wong-Baker FACES

Values

  • Infants, nonverbal, cognitively impaired
  • Behavioral observation (Face, Legs, Activity, Cry, Consolability)
  • 0–10 (each item 0–2)
  • Objective, no patient communication required

Property

FLACC Scale

Columns

  • Tool
  • Population
  • Method
  • Scale Range
  • Key Advantage

Table Title

Pain Assessment Tools Comparison

Rows

Values

  • 30–60 min (oral)
  • 1–2 hours
  • ~4 g/day (less with liver disease)
  • Hepatotoxicity (silent, dangerous)
  • Liver disease, chronic alcohol use, concurrent acetaminophen-containing products

Property

Acetaminophen

Values

  • 30 min (oral), 10 min (IV ketorolac)
  • 1–3 hours
  • Per drug; ketorolac max 5 days
  • GI bleeding/ulceration, renal impairment, increased bleeding
  • Peptic ulcer disease, renal disease, older adults, anticoagulant use; ketorolac short-term only

Property

NSAIDs (ibuprofen, naproxen, ketorolac)

Values

  • IV 5–10 min, oral 30–60 min
  • IV 15–30 min, oral 1–2 hours
  • No ceiling (titrate to effect)
  • Respiratory depression (MOST DANGEROUS), constipation, sedation, nausea, urinary retention, hypotension, miosis
  • RR < 12, severe respiratory disease, opioid allergy; start low in older adults/opioid-naive; naloxone must be available

Property

Opioids (morphine, fentanyl, hydromorphone, oxycodone)

Columns

  • Analgesic Type
  • Onset
  • Peak Effect
  • Max Daily Dose
  • Key Adverse Effects
  • When to Avoid/Use Caution

Table Title

Acetaminophen vs NSAIDs vs Opioids

Rows

Values

  • Mild
  • Acetaminophen, NSAIDs
  • Adjuvants for neuropathic pain
  • If pain remains uncontrolled after adequate trial

Property

Step 1

Values

  • Mild to Moderate
  • Weak opioids (codeine, tramadol) + non-opioids
  • Adjuvants for neuropathic pain
  • If pain remains uncontrolled after adequate trial

Property

Step 2

Values

  • Moderate to Severe
  • Strong opioids (morphine, fentanyl, hydromorphone) + non-opioids
  • Adjuvants for neuropathic pain
  • Titrate opioid dose up; palliative care no ceiling on opioid

Property

Step 3

Columns

  • Step
  • Pain Severity
  • First-Line Drugs
  • Adjuvants
  • When to Escalate

Table Title

WHO Analgesic Ladder by Pain Severity

Rows

Values

  • Need for higher doses to achieve same analgesic effect
  • Develops over days to weeks with regular use
  • Yes, by increasing dose
  • NO—tolerance does not indicate addiction

Property

Tolerance

Values

  • Body's physiologic adaptation; withdrawal (sweating, anxiety, muscle aches) occurs on abrupt cessation
  • Develops within days of regular opioid use
  • Yes, by gradual dose tapering
  • NO—physical dependence does not indicate addiction

Property

Physical Dependence

Values

  • Compulsive use despite harm, loss of control, continued use despite negative consequences—TRUE psychological disorder
  • Varies; may develop over weeks to months
  • Requires treatment (behavioral therapy, medication-assisted treatment)
  • YES—addiction is the concern; requires different treatment approach

Property

Addiction (Opioid Use Disorder)

Columns

  • Concept
  • Definition
  • Timeline
  • Reversible?
  • Indicates Addiction?

Table Title

Opioid-Related Concepts: Tolerance vs Physical Dependence vs Addiction

Rows

Values

  • < 3–6 months
  • > 3–6 months

Property

Duration

Values

  • Recent, sudden
  • Gradual or from previous acute injury

Property

Onset

Values

  • Warning of tissue injury
  • May not have clear ongoing tissue damage

Property

Cause

Values

  • Sympathetic responses: tachycardia, hypertension, diaphoresis, facial grimace, guarding
  • May be ABSENT; no outward signs

Property

Visible Signs

Values

  • Anxiety, fear
  • Depression, fatigue, sleep disruption, functional limitation, social isolation

Property

Associated Symptoms

Values

  • Pain relief as pain resolves with healing
  • Multimodal, interdisciplinary; focus on FUNCTIONAL GOALS and quality of life

Property

Management Approach

Columns

  • Feature
  • Acute Pain
  • Chronic Pain

Table Title

Acute Pain vs Chronic Pain

Rows

Values

  • Actual tissue damage or inflammation
  • Nerve damage or dysfunction

Property

Cause

Values

  • Somatic (skin, muscle, bone—well localized, aching/throbbing) and Visceral (organs—deep, cramping, poorly localized, referred)
  • Burning, shooting, tingling, electric-like sensations

Property

Types

Values

  • Post-surgical pain, fracture, appendicitis, myocardial infarction
  • Diabetic neuropathy, phantom limb pain, shingles, spinal cord injury

Property

Examples

Values

  • Usually responds well to standard analgesics
  • Often POORLY responsive to opioids alone; requires adjuvants (gabapentin, pregabalin, antidepressants)

Property

Response to NSAIDs/Opioids

Columns

  • Feature
  • Nociceptive Pain
  • Neuropathic Pain

Table Title

Nociceptive vs Neuropathic Pain

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