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NLE Gastrointestinal NursingNutritional & Metabolic SupportCheat Sheet

Nutritional & Metabolic Support cheat sheet — the reference card you wish you had on exam day. Condensed from the full study notes, this is the high-yield core of Nutritional & Metabolic Support for NLE Gastrointestinal Nursing. Download, print, revise.

Exam context

For the Philippine Nurse Licensure Examination (PNLE), Professional Regulation Commission (PRC) — Board of Nursing tests Gastrointestinal Nursing under a "Core" label, with Nutritional & Metabolic Support in the 4th slot across 4 chapters. NLE candidates must clear the 75% weighted average with no sub-test below 60% cut on the 2026 paper, which draws about 50 Gastrointestinal Nursing questions. Date to watch: Bi-annual.

Nutritional & Metabolic Support - Cheat Sheet

Your last-minute rapid-fire reference for nutritional assessment, obesity, malnutrition, enteral feeding, TPN, and bariatric nursing. Every item here can appear on the NLE. Focus on the formulas, safety rules, and clinical red flags.

Sections

Formulas

Formula

BMI = weight (kg) ÷ height (m²)

Meaning

weight in kilograms; height in meters squared

Watch Out

Height must be SQUARED. Asian populations (including Filipinos) use LOWER cut-offs: overweight ≥23, obese ≥27.5 kg/m² (not the WHO ≥25 and ≥30).

When To Use

First-line screening for malnutrition or obesity in every patient

Common Values

Value

>3.5 g/dL

Symbol

Alb

Quantity

Normal albumin level

Value

20–40 mg/dL

Symbol

PA

Quantity

Normal prealbumin level

Value

2.8–3.5 g/dL

Symbol

Alb

Quantity

Mild malnutrition (albumin)

Value

2.1–2.7 g/dL

Symbol

Alb

Quantity

Moderate malnutrition (albumin)

Value

<2.1 g/dL

Symbol

Alb

Quantity

Severe malnutrition (albumin)

Value

>1,500/mm³

Symbol

TLC

Quantity

Normal total lymphocyte count (immunity indicator)

Section Title

Nutritional Assessment & Anthropometrics

Important Facts

  • BMI categories (WHO): underweight <18.5, normal 18.5–24.9, overweight 25–29.9, obese ≥30.
  • Filipino/Asian cut-offs: underweight <18.5, normal 18.5–22.9, overweight ≥23, obese ≥27.5.
  • Prealbumin is MORE SENSITIVE to acute nutritional changes; albumin is stable and reflects chronic status.
  • Serum transferrin, total lymphocyte count (TLC <1,500/mm³ = depleted immunity), and electrolytes complete the picture.
  • Anthropometrics + biochemical + clinical signs = complete nutritional assessment; never use one measure alone.
  • Edema can mask true weight loss (patient looks heavier but is malnourished) — check for muscle wasting and skin turgor.
  • Fever, stress, and wounds increase caloric needs; adjust nutritional support accordingly.

Key Definitions

Term

Prealbumin (Transthyretin)

Example

Falls within 24–48 hours of poor intake; useful for monitoring refeeding response.

Definition

Serum protein with half-life ~2 days; reflects RECENT nutritional status and acute changes in intake.

Term

Albumin

Example

Normal >3.5 g/dL; low indicates chronic malnutrition or liver disease; slower to change.

Definition

Serum protein with half-life ~3 weeks; reflects LONG-TERM nutritional status.

Term

Marasmus

Example

Malnourished patient on prolonged starvation diet.

Definition

Chronic total energy deficit; severe wasting with low weight and minimal subcutaneous fat.

Term

Kwashiorkor

Example

Young child with inadequate protein but some carbohydrate intake.

Definition

Severe protein deficit; muscle wasting with peripheral edema, ascites, and deceptively preserved or increased weight.

Term

Unintentional Weight Loss (Significant)

Example

Patient reports loss of 4 kg in 3 weeks → investigate cause and start nutritional support.

Definition

>5% in 1 month OR >10% in 6 months; red flag for malnutrition and poor prognosis.

Diagrams To Know

  • Nutritional assessment pyramid (anthropometric → biochemical → clinical/dietary → functional status).
  • BMI classification chart for standard and Asian populations side-by-side.

Common Values

Value

0.5–1 kg/week

Symbol

WL

Quantity

Sustainable weekly weight loss

Value

≥40 or ≥35 with comorbidities

Symbol

BMI

Quantity

BMI threshold for bariatric surgery consideration (severe obesity)

Section Title

Obesity

Important Facts

  • Obesity is MULTIFACTORIAL: genetic predisposition, behavioral habits (diet, sedentary), and environmental factors (food access, stress).
  • Comorbidities: type 2 diabetes, hypertension, dyslipidemia, coronary artery disease (CAD), obstructive sleep apnea (OSA), fatty liver disease (NAFLD), osteoarthritis, and cancer (breast, colon, endometrial).
  • Management LADDER: (1) diet + physical activity + behavior change FIRST, (2) pharmacotherapy if needed, (3) bariatric surgery for severe/refractory obesity.
  • Target weight loss: ~0.5–1 kg/week is SUSTAINABLE; crash dieting fails long-term and harms metabolism.
  • STIGMA REDUCES ENGAGEMENT: use weight-inclusive, non-judgmental language; avoid blame; emphasize health, not appearance.
  • Nursing role: assess comorbidities, teach realistic goals, provide motivation and support, and screen for sleep apnea (critical in Philippine context where OSA is often missed).

Key Definitions

Term

Obesity

Example

Adult with BMI 32 kg/m² and hypertension, sleep apnea, and type 2 diabetes.

Definition

Excess body fat (BMI ≥30 globally; ≥27.5 in Asian/Filipino populations) increasing risk of metabolic and cardiovascular disease.

Term

Orlistat

Example

Patient taking orlistat may experience oily stool and fat-soluble vitamin (A, D, E, K) malabsorption.

Definition

Lipase inhibitor; reduces fat absorption in the GI tract; used for weight management in obese patients.

Term

GLP-1 Agonists (Liraglutide, Semaglutide)

Example

Semaglutide (Ozempic, Wegovy) is gaining use in obesity management; monitor for pancreatitis and thyroid effects.

Definition

Incretin mimetics; increase satiety and slow gastric emptying; promote modest weight loss and glycemic control.

Diagrams To Know

  • Obesity management algorithm (diet + activity → pharmacotherapy → surgery).
  • Obesity-related comorbidity web (central obesity, insulin resistance, inflammation).

Common Values

Value

>5%

Symbol

WL%

Quantity

Significant unintentional weight loss (1 month)

Value

>10%

Symbol

WL%

Quantity

Significant unintentional weight loss (6 months)

Value

10–15 kcal/kg or ~50% of estimated need

Symbol

kcal

Quantity

Starting calorie target in refeeding (Day 1)

Value

<2.5 mg/dL (high risk <1 mg/dL)

Symbol

PO4

Quantity

Phosphate critical low level (refeeding risk)

Value

<2.5 mEq/L (severe)

Symbol

K+

Quantity

Potassium critical low level

Section Title

Malnutrition & Refeeding Syndrome

Important Facts

  • REFEEDING SYNDROME PREVENTION is the #1 safety priority: START LOW, INCREASE SLOWLY; give THIAMINE before/with first feeding.
  • In refeeding, carbohydrate (glucose) triggers INSULIN surge → shifts phosphate, potassium, and magnesium INTRACELLULARLY → SEVERE SERUM DEFICITS.
  • Early signs of refeeding syndrome: weakness, cardiac arrhythmias, respiratory distress, confusion — often appear 24–48 hours after aggressive feeding starts.
  • Electrolyte monitoring (phosphate, potassium, magnesium) is MANDATORY in first 3–5 days of feeding a malnourished patient.
  • Manifestations of malnutrition: weight loss, muscle wasting, weakness/fatigue, poor wound healing, edema (hypoalbuminemia), impaired immunity (recurrent infections), anemia, and micronutrient deficiencies.
  • Assessment triggers: BMI <18.5, unintentional weight loss >5% in 1 month or >10% in 6 months, prealbumin <20 mg/dL, albumin <3.5 g/dL.
  • Treatment principle: 'Oral route first' — small frequent energy-dense meals + oral nutritional supplements (if tolerated) before enteral/parenteral support.
  • Causes to investigate: inadequate intake (dysphagia, pain, depression), malabsorption (diarrhea, Crohn's, celiac), increased losses (vomiting, fistula), or increased needs (fever, wound, sepsis).

Key Definitions

Term

Protein-Energy Malnutrition (PEM)

Example

Hospitalized patient with reduced oral intake for >2 weeks, low prealbumin, and low lymphocyte count.

Definition

Insufficient intake of protein and/or calories resulting in weight loss, muscle wasting, and impaired immunity; spectrum from marasmus to kwashiorkor.

Term

Refeeding Syndrome (HIGH-YIELD)

Example

Starved patient started on 2,000 kcal/day → sudden fall in phosphate, potassium, magnesium within 24–48 hours; risk of cardiac arrest.

Definition

Dangerous metabolic complication when a severely malnourished patient is fed too aggressively → HYPOphosphatemia, HYPOkalemia, HYPOmagnesemia, and thiamine depletion → cardiac arrhythmias, respiratory failure, and death.

Term

Thiamine (Vitamin B1) Depletion

Example

Malnourished patient fed without thiamine supplementation → confusion, ataxia, ophthalmoplegia (Wernicke).

Definition

Loss of a critical cofactor for glucose metabolism; causes Wernicke encephalopathy and 'wet beriberi' (heart failure); especially critical in refeeding.

Diagrams To Know

  • Refeeding syndrome timeline: starvation → feeding started → 24–48 h → electrolyte crash → cardiac/respiratory crisis.
  • Thiamine and B-vitamin depletion cascade in refeeding.

Reactions Or Equations

Note

This is the MECHANISM of refeeding syndrome; understanding it is key to prevention (gradual feeding, electrolyte replacement, thiamine supplementation).

Equation

Insulin surge → glucose uptake → phosphate/K+/Mg2+ shift intracellular → SERUM HYPO state

Conditions

Occurs when a starved, insulin-resistant patient is suddenly fed carbohydrate (especially IV dextrose or aggressive feeding); glucose uptake resumes and insulin acts.

Common Values

Value

≤5.5

Symbol

pH

Quantity

Gastric pH (indicates gastric placement)

Value

20–30 mL/h

Symbol

Rate

Quantity

Initial infusion rate (conservative start)

Value

20–30 mL/h every 4–8 h

Symbol

Adv

Quantity

Rate advancement (safe increment)

Value

30–45°

Symbol

Angle

Quantity

HOB elevation (aspiration prevention)

Value

30–60 minutes

Symbol

Time

Quantity

Duration of HOB elevation after feed

Value

>250 mL (institution-specific; some use >200 mL)

Symbol

GRV

Quantity

Gastric residual volume threshold (hold feed if exceeded)

Value

4–8 hours (then discard)

Symbol

Time

Quantity

Formula hang time (open system, room temperature)

Section Title

Enteral Nutrition (Tube Feeding)

Important Facts

  • GOLDEN RULE: 'If the gut works, USE IT' — enteral feeding preserves gut integrity, is cheaper, and has fewer complications than TPN.
  • TUBE PLACEMENT VERIFICATION (CRITICAL):
  • • X-ray confirms initial placement (gold standard).
  • • Before EVERY feed/medication: aspirate gastric contents, check pH ≤5.5 (gastric), observe appearance.
  • • Auscultation ('whooshing' sound) is UNRELIABLE and should NOT be used alone.
  • • Never assume placement without verification — aspiration into lungs is a serious complication.
  • ASPIRATION PREVENTION (TOP PRIORITY):
  • • Keep head of bed elevated 30–45° during feeding AND for 30–60 minutes AFTER.
  • • Use continuous infusion (pump) rather than bolus if high aspiration risk.
  • • Monitor for signs of aspiration: cough, fever, respiratory distress, new infiltrate on CXR.
  • TUBE CARE & MAINTENANCE:
  • • Flush with water BEFORE and AFTER every feed and medication (prevents clogging).
  • • Give medications SEPARATELY, each one flushed independently.
  • • Do NOT crush enteric-coated or sustained-release tablets (coat bypassed, absorption altered).
  • • Administer liquid formulations of medications when possible.
  • FORMULA DELIVERY METHODS:
  • • Bolus/intermittent (4–6 times daily): closest to normal eating, used for gastric feeding, faster completion.
  • • Continuous (pump over 18–24 hours): better tolerated, preferred for jejunal feeding and critically ill patients.
  • • Start slow (20–30 mL/h), advance by 20–30 mL/h every 4–8 h as tolerated to reduce GI upset.
  • FORMULA CONTAMINATION & STORAGE:
  • • Use clean (non-sterile) technique for administration.
  • • Limit hang time per protocol: typically 4–8 hours for open systems; refrigerate unused formula.
  • • Discard formula at room temperature after 4 hours to prevent bacterial growth.
  • COMPLICATIONS & MANAGEMENT:
  • • Aspiration (MOST SERIOUS): elevate HOB, verify placement, consider continuous infusion or jejunal route.
  • • Diarrhea: hyperosmolar formula, fast rate, antibiotics, C. diff risk — slow rate, add fiber, consider elemental formula.
  • • Tube clogging: flush with warm water, use enzymatic declogger if needed.
  • • Tube displacement: verify placement before each use; secure tube well.
  • • Dumping-type symptoms: switch to lower osmolality formula, slower infusion rate, smaller frequent feeds.

Key Definitions

Term

Enteral Nutrition

Example

Patient with CVA and dysphagia receiving nutrition via nasogastric tube.

Definition

Delivery of nutritionally complete formula via the GI tract (mouth, nose, stomach, or small bowel); preferred route when gut is functional.

Term

Nasogastric Tube (NGT)

Example

Post-op patient unable to eat; NGT placed for 3 days while bowel function returns.

Definition

Short-term feeding tube (typically <4 weeks) placed through nose into stomach; easy insertion, may reflux.

Term

Percutaneous Endoscopic Gastrostomy (PEG)

Example

Patient with ALS and progressive dysphagia → PEG placed for ongoing nutritional support.

Definition

Long-term feeding tube (>4–6 weeks) placed surgically/endoscopically directly into stomach; more comfortable and secure.

Term

Gastric Residual Volume (GRV)

Example

If GRV >250 mL, hold feed, recheck in 1 hour, investigate for slow emptying or intolerance.

Definition

Amount of undigested formula remaining in stomach before next feed; checked to assess tolerance and prevent aspiration.

Term

Polymeric Formula

Example

Most common enteral formula; suitable for non-restrictive diets.

Definition

Intact protein, intact fat, complex carbohydrate; standard formula for patients with normal GI function.

Term

Elemental/Semi-Elemental Formula

Example

Patient with pancreatic insufficiency or Crohn's disease with severe malabsorption.

Definition

Predigested protein (amino acids/dipeptides), simple carbs, minimal fat; for impaired digestion or absorption.

Term

Dumping Syndrome (Enteral Feeding)

Example

Patient on continuous high-osmolality feed → diarrhea and cramping; switch to lower osmolality or slower infusion rate.

Definition

Rapid gastric emptying into small bowel → osmotic diarrhea, abdominal cramping, weakness, tachycardia, and sweating 30–60 min after feed (not the same as post-bariatric dumping, but similar mechanism).

Diagrams To Know

  • Tube feeding setup flowchart: assess → insert → verify → deliver → monitor → troubleshoot.
  • Decision tree for choosing formula type (polymeric vs. elemental vs. disease-specific).
  • Aspiration prevention checklist (HOB angle, tube verification, flush schedule, tube care).

Common Values

Value

20–35%

Symbol

Dex%

Quantity

TPN dextrose concentration (high-osmolarity central line)

Value

<12.5% (max osmolarity ~600 mOsm/L)

Symbol

Dex%

Quantity

PPN dextrose concentration (peripheral, lower osmolarity)

Value

Every 4–6 hours (or per sliding scale)

Symbol

Freq

Quantity

Blood glucose monitoring frequency on TPN (initial)

Value

40–50 mL/h, advance gradually

Symbol

Rate

Quantity

Typical initial TPN infusion rate

Value

10% dextrose (D10W) at SAME rate as TPN was running

Symbol

D10W

Quantity

Dextrose infusion increment if rebound hypoglycemia suspected

Value

Every 24 hours (ASEPTIC technique critical)

Symbol

Interval

Quantity

TPN tubing change interval

Value

Every 7 days or if wet/soiled

Symbol

Interval

Quantity

Catheter dressing change interval

Section Title

Total Parenteral Nutrition (TPN)

Important Facts

  • TPN INDICATION: GI tract CANNOT be used or inadequate (massive bowel resection, severe pancreatitis, prolonged ileus, intractable vomiting, high-output fistula).
  • TPN MUST RUN THROUGH A CENTRAL LINE — the hyperosmolar dextrose (often 20–35%) would sclerose and damage a peripheral vein.
  • SAFETY RULE #1 — NEVER STOP TPN ABRUPTLY:
  • • Sudden cessation → rebound hypoglycemia (pancreas still secreting insulin).
  • • ALWAYS TAPER the rate down gradually (e.g., reduce by 25% every 1–2 hours).
  • • If the next bag is delayed/unavailable, hang 10% dextrose (D10W) at the SAME rate as TPN was running to prevent glucose crash.
  • • NEVER substitute plain saline (0.9% NaCl) — this will cause hypoglycemia.
  • SAFETY RULE #2 — USE AN INFUSION PUMP (not gravity) and STRICT ASEPTIC TECHNIQUE:
  • • TPN is a perfect culture medium for bacteria and fungi → CRBSI is the top complication.
  • • Meticulous hand hygiene, sterile dressing, and tubing changes per protocol (typically every 24 h for TPN tubing).
  • SAFETY RULE #3 — MONITOR BLOOD GLUCOSE (every 4–6 hours initially, at least daily once stable):
  • • Hyperglycemia is common early (stress response, dextrose load); use sliding-scale insulin as ordered.
  • • Avoid 'catching up' if behind — do NOT speed up the infusion; this destabilizes glucose control and risks hyperglycemic crisis.
  • • Keep the ORDERED RATE steady; use a pump with an alarm.
  • SAFETY RULE #4 — DEDICATED ACCESS:
  • • Do NOT use the TPN line for other IV medications, blood draws, or CVP readings unless a multi-lumen catheter with a DESIGNATED lumen is available.
  • • Do NOT piggyback other meds into TPN tubing (precipitate risk, incompatibility).
  • COMPLICATIONS & MONITORING:
  • • CATHETER-RELATED:
  • - Air embolism: during tubing changes — position patient LEFT side, head DOWN (Trendelenburg), have patient perform VALSALVA during connection; prevent by pinching catheter before disconnection.
  • - Pneumothorax: during insertion (rare); watch for dyspnea, decreased breath sounds.
  • - Thrombosis: swelling, pain, positional occlusion; may require thrombolytics or catheter removal.
  • • METABOLIC:
  • - Hyperglycemia (early, most common): insulin adjustment needed.
  • - Hypoglycemia (if TPN stopped abruptly or rate cut): taper TPN, use D10W, monitor closely.
  • - Refeeding syndrome (if patient was malnourished): gradual calorie increase, electrolyte monitoring, thiamine supplementation.
  • - Hepatic dysfunction (long-term TPN >7–14 days): monitor ALT, AST, bilirubin; cholestasis risk; rotate amino acid source if needed.
  • • INFECTIOUS:
  • - CRBSI: fever, positive blood culture; suspect if fever develops on TPN; remove/replace catheter; broad-spectrum antibiotics.
  • DAILY MONITORING CHECKLIST:
  • • Weight (daily), strict I&O, blood glucose (every 4–6 h), electrolytes (daily), phosphate/magnesium (daily × 3–5 days, then 2–3×/week), liver function (2–3×/week), triglycerides (weekly; lipid emulsion risk).
  • • Inspect catheter site for erythema, warmth, drainage, induration.
  • • Assess for signs of infection (fever, chills, malaise) or metabolic derangement (confusion, weakness, cardiac dysrhythmia).
  • TRANSITIONING OFF TPN:
  • • As gut recovers, wean TPN GRADUALLY while advancing enteral/oral intake.
  • • Taper TPN rate down (do not stop abruptly) as enteral intake increases.
  • • Continue blood glucose monitoring during transition (insulin secretion lags behind falling glucose load).
  • • Confirm patient is meeting ≥50–75% of needs orally/enterally before discontinuing TPN completely.

Key Definitions

Term

Total Parenteral Nutrition (TPN)

Example

Patient with extensive small-bowel resection (short-bowel syndrome) unable to absorb adequate nutrients; TPN via central line.

Definition

Complete intravenous nutrition delivered when the GI tract cannot be used; contains dextrose (hyperosmolar), amino acids, lipids, electrolytes, vitamins, and trace elements.

Term

Central Venous Line (CVL) / Central Catheter

Example

Subclavian CVC inserted for TPN in patient with pancreatic necrosis unable to tolerate enteral feeding.

Definition

Catheter with tip in a central vein (subclavian, internal jugular, PICC); required for TPN because high dextrose concentration is hyperosmolar and scleroses peripheral veins.

Term

Peripheral Parenteral Nutrition (PPN)

Example

Temporary 48-hour PN while awaiting central line placement.

Definition

Lower-concentration PN via peripheral IV (dextrose <12.5%, osmolality <600 mOsm/L); used only SHORT-TERM when central access is contraindicated.

Term

Rebound Hypoglycemia

Example

TPN running at 100 mL/h (delivering ~100 g/h of dextrose) suddenly stopped → blood glucose crashes within minutes; high risk of seizure or cardiac event.

Definition

Sudden drop in blood glucose when TPN is stopped abruptly; occurs because the pancreas is still secreting insulin in response to high glucose load.

Term

Catheter-Related Bloodstream Infection (CRBSI)

Example

Patient on TPN for 2 weeks develops fever, positive blood culture, and elevated WBC; CVC removed and sent for culture.

Definition

Infection (bacterial or fungal) at the TPN catheter site or bloodstream from contamination; most common serious complication of TPN.

Diagrams To Know

  • TPN composition pyramid (dextrose + amino acids + lipids + electrolytes + vitamins + trace elements).
  • TPN troubleshooting flowchart: hyperglycemia → hypo → infection → metabolic derangement.
  • Air embolism emergency response (LEFT lateral, Trendelenburg, Valsalva, O2, call team).

Reactions Or Equations

Note

Example: 20% dextrose at 100 mL/h = 400 kcal from dextrose alone. High-concentration TPN requires careful glucose monitoring.

Equation

TPN glucose delivery (g/h) = [dextrose concentration (%) / 100] × infusion rate (mL/h) ÷ 5

Conditions

Used to estimate carbohydrate load and anticipate hyperglycemia risk; useful for insulin titration.

Note

This is the MECHANISM of rebound hypoglycemia; prevention is KEY: always taper, always use D10W if bag delayed.

Equation

If TPN stopped abruptly → insulin still acting on residual circulating glucose + no new glucose infusion = REBOUND HYPOGLYCEMIA

Conditions

Occurs when TPN is discontinued without tapering or glucose supplementation; especially risky if patient on insulin.

Common Values

Value

~30 mL

Symbol

Vol

Quantity

Gastric pouch capacity (immediate post-op)

Value

~150 mL

Symbol

Vol

Quantity

Gastric pouch capacity (after 3–6 months adaptation)

Value

≥40 (or ≥35 with comorbidities)

Symbol

BMI

Quantity

BMI threshold for bariatric surgery (severe obesity)

Value

1–2 kg/week

Symbol

WL

Quantity

Typical weekly weight loss post-bariatric (months 2–6)

Value

15–30 minutes

Symbol

Time

Quantity

Dumping syndrome onset (after eating)

Value

Days 1–5 (highest risk Days 2–3)

Symbol

Window

Quantity

Anastomotic leak risk window post-op

Section Title

Bariatric Surgery & Post-Operative Nursing

Important Facts

  • BARIATRIC SURGERY INDICATIONS:
  • • BMI ≥40 kg/m² (or ≥35 kg/m² with obesity-related comorbidities: diabetes, hypertension, sleep apnea, CAD).
  • • Failed conservative management (diet + exercise) for ≥6 months.
  • • Psychological readiness; commitment to lifelong dietary adherence and supplementation.
  • POST-OP NURSING PRIORITIES:
  • • ANASTOMOTIC LEAK (EARLY RECOGNITION — LIFE-THREATENING):
  • - CLASSIC TRIAD: fever + tachycardia (>120) + acute abdominal pain.
  • - Also watch for: restlessness, increased respiratory rate, elevated WBC with left shift.
  • - Can occur Day 1–5 post-op; suspect even with subtle signs.
  • - Management: NPO, broad-spectrum antibiotics, emergency imaging (CT with oral contrast), surgical re-exploration likely.
  • • AIRWAY/RESPIRATORY:
  • - Many bariatric patients have sleep apnea (undiagnosed or known).
  • - Post-op risk: opioid use depresses respiratory drive in apneic patient → hypoxia.
  • - Monitor O2 saturation closely; consider ICU stay if severe OSA; use analgesia cautiously.
  • • DEEP VEIN THROMBOSIS (DVT) & VENOUS THROMBOEMBOLISM (VTE) PROPHYLAXIS:
  • - Bariatric patients at high VTE risk (obesity, surgery, immobility).
  • - Enoxaparin/heparin + early ambulation + compression stockings.
  • • NUTRITION & FEEDING PROGRESSION:
  • - Post-op diet is staged: clear liquids → full liquids → soft foods → regular (high-protein, small-volume meals).
  • - Strict portion control (pouch capacity ~30 mL initially, gradually stretches to ~150 mL).
  • - NO straws (increase swallowing of air); sip slowly; separate food and fluids.
  • • PAIN MANAGEMENT:
  • - Avoid NSAIDs (increase leak risk early post-op).
  • - Acetaminophen and opioids (short-term); taper opioids to avoid dependency and constipation.
  • DUMPING SYNDROME PREVENTION:
  • • Eat SMALL frequent meals (4–6 meals/day, 1–1.5 cups per meal).
  • • Avoid SIMPLE SUGARS and high-osmolarity foods (sweets, sugary drinks, fruit juices).
  • • Eat PROTEIN and COMPLEX CARBS (higher satiety, slower gastric emptying).
  • • DRINK FLUIDS BETWEEN MEALS, NOT WITH MEALS (dilutes food, increases osmolarity, speeds emptying).
  • • Lie down 30 minutes after eating (slows gastric emptying, reduces dumping).
  • • Adequate fiber (prevents both constipation and diarrhea).
  • LIFELONG NUTRITIONAL DEFICIENCIES (HIGH-YIELD):
  • • Bariatric surgery causes malabsorption due to reduced gastric capacity and bypassed bowel.
  • • MANDATORY lifelong supplementation (adherence critical for health):
  • - IRON (especially women of child-bearing age): microcytic anemia, fatigue, pallor; check ferritin annually.
  • - VITAMIN B12 (loss of intrinsic factor + reduced stomach acid + bypassed ileum): macrocytic anemia, neurologic symptoms (paresthesia, ataxia, dementia if severe); injections or sublingual forms often needed; check serum B12 and methylmalonic acid/homocysteine.
  • - FOLATE: macrocytic anemia; often depleted alongside B12.
  • - CALCIUM + VITAMIN D: reduced absorption (D aids Ca absorption); risk of osteomalacia, tetany, bone loss; monitor alkaline phosphatase, 25-OH vitamin D.
  • - THIAMINE (B1): Wernicke encephalopathy risk if depleted; ensure supplementation.
  • - Zinc, copper, selenium (trace elements).
  • • Annual monitoring: CBC, vitamin B12, folate, iron studies (ferritin, TIBC), alkaline phosphatase, calcium, vitamin D, albumin.
  • POST-BARIATRIC NUTRITIONAL TEACHING:
  • • Chew thoroughly (prevent obstruction, aid digestion).
  • • Eat slowly (allow satiety signals to reach brain); ~20–30 min per meal.
  • • Protein FIRST (every meal must contain protein to prevent muscle loss and maintain satiety).
  • • Take multivitamin + minerals DAILY (bariatric-specific formulation if possible).
  • • Attend support groups and follow-up appointments (improve long-term outcomes).

Key Definitions

Term

Bariatric Surgery

Example

Patient with BMI 48, type 2 diabetes, hypertension, sleep apnea — not responding to diet/exercise → gastric bypass approved by multidisciplinary team.

Definition

Weight-reduction surgery (e.g., sleeve gastrectomy, Roux-en-Y gastric bypass); indicated for severe/refractory obesity (typically BMI ≥40, or ≥35 with comorbidities) when medical management fails.

Term

Sleeve Gastrectomy

Example

Less anatomically complex than bypass; lower nutrient malabsorption risk.

Definition

Vertical reduction of stomach (removing ~75%); reduces gastric volume and decreases ghrelin production → early satiety and reduced hunger.

Term

Roux-en-Y Gastric Bypass

Example

More weight loss than sleeve; higher risk of nutrient deficiencies (B12, iron, folate, calcium, vitamin D); dumping syndrome common.

Definition

Creation of small gastric pouch (~30 mL); small bowel (jejunum) anastomosed directly to pouch, bypassing stomach and part of small bowel → restriction + malabsorption.

Term

Anastomotic Leak

Example

Post-op day 2: sudden fever, tachycardia (HR >120), acute abdominal pain, restlessness, elevated WBC, left shift → suspect leak; urgent imaging and surgical exploration.

Definition

Rupture or breakdown of the surgical anastomosis (connection between stomach pouch and bowel); most serious early post-op complication.

Term

Dumping Syndrome (Post-Bariatric)

Example

Patient eats 200 mL of sweet juice post-bypass → 15 min later: cramping, palpitations, diaphoresis, urgency to defecate.

Definition

Rapid gastric emptying of hyperosmolar chyme into small bowel; triggers osmotic diarrhea, vasoactive substance release → cramping, diarrhea, tachycardia, sweating, dizziness 15–30 min after eating.

Diagrams To Know

  • Roux-en-Y bypass anatomy: gastric pouch + limb bypass diagram.
  • Anastomotic leak emergency response (fever + tachy + pain → imaging → surgery).
  • Dumping syndrome timeline and prevention strategy flowchart.

Common Values

Value

50–150 mcg/dL

Symbol

Fe

Quantity

Normal serum iron

Value

30–300 ng/mL

Symbol

Ferr

Quantity

Normal ferritin

Value

>200 pg/mL (some say >300)

Symbol

B12

Quantity

Normal serum B12

Value

>5.4 ng/mL

Symbol

Fol

Quantity

Normal folate

Value

>30 ng/mL (optimal >40)

Symbol

Vit D

Quantity

Normal 25-OH vitamin D

Value

8.5–10.5 mg/dL

Symbol

Ca

Quantity

Normal serum calcium

Section Title

Micronutrient Deficiencies — Recognition & Clinical Picture

Important Facts

  • IRON DEFICIENCY: microcytic, hypochromic anemia; fatigue, weakness, dyspnea; pallor, tachycardia; koilonychia (spoon nails); elevated TIBC, low ferritin/serum iron.
  • B12 DEFICIENCY: macrocytic anemia; fatigue, weakness, glossitis (sore tongue); NEUROLOGIC: paresthesia (feet/hands), ataxia, 'stocking-glove' distribution; can progress to dementia if untreated; elevated homocysteine, methylmalonic acid; low serum B12.
  • FOLATE DEFICIENCY: macrocytic anemia (indistinguishable from B12 deficiency on CBC alone — must check B12 and folate levels); often co-occurs with B12 deficiency post-bariatric.
  • VITAMIN D & CALCIUM: bone pain, muscle cramps, tetany (severe hypo-Ca), osteomalacia (soft bones, fractures); elevated alkaline phosphatase; low 25-OH vitamin D (<20 ng/mL); low serum calcium.
  • THIAMINE: EMERGENCY deficiency (Wernicke encephalopathy): acute confusion, ophthalmoplegia (can't move eyes), ataxia (can't walk) — requires URGENT thiamine replacement IV/IM (can be irreversible if delayed); chronic deficiency (wet beriberi): heart failure, peripheral neuropathy.
  • VITAMIN C: poor wound healing, bleeding/perifollicular hemorrhages, perifollicular hemorrhages, anemia (affects iron absorption); scurvy is rare in developed countries but seen in severe malnutrition.
  • VITAMIN A: night blindness (first sign), dry skin (xerosis), increased respiratory/GI infections (immune impairment).
  • ZINC: impaired wound healing, altered taste (hypogeusia), dermatitis (especially perioral, around eyes).
  • Clinical recognition is KEY on NLE: must be able to match symptoms to deficiency (e.g., 'patient with post-bypass surgery, neurologic paresthesia and ataxia' → think B12 deficiency).

Key Definitions

Term

Iron Deficiency Anemia

Example

Patient with low ferritin and serum iron, low hemoglobin, elevated TIBC; symptoms: fatigue, pallor, dyspnea on exertion, koilonychia (spoon nails).

Definition

Inadequate hemoglobin due to low iron stores; common in malnutrition, chronic bleeding, and post-bariatric malabsorption.

Term

Vitamin B12 Deficiency

Example

Post-bariatric patient with low B12 (injection-dependent), elevated homocysteine/methylmalonic acid; neurologic: paresthesia in feet, ataxia, cognitive changes.

Definition

Lack of cobalamin; impairs DNA synthesis and myelin formation → macrocytic anemia + neurologic symptoms.

Term

Vitamin D & Calcium Deficiency

Example

Post-bariatric patient with low 25-OH vitamin D and alkaline phosphatase elevation; complains of bone pain, muscle cramps, weakness.

Definition

Reduced calcium absorption and mineralization; leads to osteomalacia (soft bones), tetany, and fractures.

Term

Thiamine (B1) Deficiency / Wernicke Encephalopathy

Example

Malnourished patient started on aggressive feeding without thiamine → within 48 h: confusion, nystagmus, inability to move eyes laterally (ophthalmoplegia), ataxia (can't walk).

Definition

Critical cofactor for carbohydrate metabolism; deficiency causes acute confusion, ophthalmoplegia, ataxia; classically seen in alcoholics and refeeding.

Term

Vitamin C Deficiency / Scurvy

Example

Elderly patient with poor diet and malnutrition; bleeding gums, perifollicular hemorrhages, poor wound healing post-op.

Definition

Impaired collagen synthesis → poor wound healing, bleeding gums, petechiae, anemia.

Term

Vitamin A Deficiency

Example

Patient with chronic diarrhea/malabsorption; night blindness (can't see in dim light), dry skin, increased infections.

Definition

Impaired vision, immune function, and skin integrity; causes night blindness and dry skin (xerosis).

Diagrams To Know

  • Micronutrient deficiency symptom reference card (iron → B12 → folate → vitamin D → thiamine → vitamin C → vitamin A — each with hallmark signs).
  • Lab values quick reference (low ferritin, low B12, low folate, low 25-OH vitamin D, elevated alkaline phosphatase, etc.).

Must Remember

Item

BMI = weight (kg) ÷ height (m²); Use LOWER Asian/Filipino cut-offs: overweight ≥23, obese ≥27.5 kg/m² (NOT WHO standard ≥25 and ≥30)

Rank

1

Item

REFEEDING SYNDROME is a deadly complication when a starved patient is fed too aggressively → HYPOphosphatemia, HYPOkalemia, HYPOmagnesemia + thiamine depletion. PREVENTION: START LOW and SLOW; GIVE THIAMINE before/with feeding; MONITOR & REPLACE electrolytes closely × 5 days.

Rank

2

Item

GOLDEN RULE: 'If the gut works, USE IT' — enteral feeding is ALWAYS preferred over TPN (preserves gut, cheaper, fewer complications).

Rank

3

Item

TPN MUST RUN THROUGH A CENTRAL VENOUS LINE (not peripheral) because the dextrose is hyperosmolar and would sclerose a peripheral vein. Use pump + strict aseptic technique (CRBSI is the top complication).

Rank

4

Item

NEVER STOP TPN ABRUPTLY → REBOUND HYPOGLYCEMIA (pancreas still secreting insulin). ALWAYS TAPER and if the next bag is delayed, hang 10% dextrose (D10W) at the SAME rate. NEVER substitute plain saline.

Rank

5

Item

Tube feeding PLACEMENT VERIFICATION: X-ray confirms initial placement; before EVERY feed/med: aspirate & check pH ≤5.5 (gastric). Auscultation is UNRELIABLE — do NOT use alone. Always verify before feeding to prevent aspiration.

Rank

6

Item

ASPIRATION PREVENTION (enteral): Keep HOB elevated 30–45° DURING and FOR 30–60 MINUTES AFTER feeding. This is the #1 nursing action to prevent the most serious enteral complication.

Rank

7

Item

AIR EMBOLISM during TPN tubing change: Position patient LEFT LATERAL, Trendelenburg (head DOWN), have patient VALSALVA during connection. Prevention: never allow air into central line.

Rank

8

Item

DUMPING SYNDROME (post-bariatric): Small frequent meals, LOW simple carbs, HIGH protein/fat, DRINK FLUIDS BETWEEN (NOT WITH) meals, lie down 30 min after eating. Explain this to EVERY post-bariatric patient.

Rank

9

Item

Post-bariatric LIFELONG DEFICIENCIES: Mandatory supplementation of B12, iron, folate, calcium, vitamin D, thiamine. Annual monitoring labs. Patient MUST understand this is lifelong, not temporary.

Rank

10

Last Minute Tips

Tip

On exam, recognize REFEEDING SYNDROME presentation: malnourished patient + aggressive feeding → HYPOphosphatemia + weakness + arrhythmias. The answer is always 'start feeding slowly, give thiamine, replace electrolytes' — this is tested EVERY year on NLE.

Tip

TPN questions almost always test the safety rule: 'Do NOT stop TPN abruptly.' If a scenario shows TPN being discontinued, the correct answer is 'taper and use D10W' — NOT to stop and observe. This is a high-yield trap.

Tip

When enteral feeding complications are presented (diarrhea, aspiration, tube clogging), the answers usually revolve around: verify placement first, slow the rate, flush the tube, elevate HOB, and assess tolerance. Master these steps.

Tip

Bariatric surgery questions test post-op complications: recognize ANASTOMOTIC LEAK as the most serious (fever + tachycardia + acute abdominal pain = EMERGENCY). Also know dumping syndrome management (small meals, avoid sugars, fluids between meals, lie down after eating) — this is heavily tested.

Tip

Micronutrient deficiency matching is a favorite NLE item: night blindness (vitamin A), paresthesia + ataxia (B12), poor wound healing (vitamin C/zinc), bone pain (vitamin D/calcium). Practice matching symptoms to deficiencies — do mock questions until automatic.

Comparison Tables

Rows

Values

  • Total calories (ENERGY deficit)
  • PROTEIN with some calories
  • Both protein AND calories

Property

Primary deficiency

Values

  • Severe wasting; very low weight
  • Moderate; deceptively normal/high weight
  • Variable; depends on timeline

Property

Weight loss

Values

  • SEVERELY depleted (visible wasting)
  • Muscle wasting but fat preserved
  • Moderate depletion of both

Property

Muscle & subcutaneous fat

Values

  • ABSENT (fluid shifts extracellular → dehydrated look)
  • PRESENT (periorbital, peripheral, ascites)
  • Variable; often present

Property

Edema

Values

  • May be low but often RELATIVELY preserved (catabolism slower)
  • SEVERELY low (hypoalbuminemia)
  • Low

Property

Albumin & serum proteins

Values

  • Fine; may lose color (flag sign)
  • Flaky dermatitis, hair easily pulled (flag sign classic)
  • Both may occur

Property

Hair & skin changes

Values

  • Prolonged starvation diet
  • Infection, diarrhea + low protein intake
  • Hospitalized, chronically ill (most common in hospitals)

Property

Common setting

Columns

  • Feature
  • Marasmus
  • Kwashiorkor
  • Mixed Malnutrition

Table Title

Marasmus vs Kwashiorkor vs Mixed Malnutrition

Rows

Values

  • Via GI tract (mouth, nose, stomach, bowel)
  • Intravenous (central line)

Property

Route

Values

  • GI tract functional (can absorb); preferred
  • GI tract CANNOT be used (obstruction, severe pancreatitis, massive resection)

Property

When used

Values

  • NGT (short-term) or PEG/jejunostomy (long-term)
  • CENTRAL VENOUS LINE (mandatory — hyperosmolar dextrose)

Property

Access required

Values

  • CHEAPER
  • EXPENSIVE

Property

Cost

Values

  • PRESERVED (normal gut function maintained)
  • May ATROPHY (gut disuse)

Property

Gut integrity

Values

  • Lower (natural barrier intact)
  • HIGHER (central line CRBSI, sepsis major complication)

Property

Infection risk

Values

  • Yes (HOB 30–45°, verify placement, monitor residuals)
  • No (bypasses GI tract)

Property

Aspiration risk

Values

  • Diarrhea, dumping, tube obstruction
  • Hyperglycemia, rebound hypoglycemia if stopped abruptly, refeeding syndrome, hepatic dysfunction

Property

Metabolic complications

Values

  • Check tube placement before feeds, monitor GRV, assess tolerance
  • Daily: glucose, electrolytes, phosphate, liver function; strict aseptic technique

Property

Monitoring frequency

Columns

  • Aspect
  • Enteral Feeding
  • Total Parenteral Nutrition (TPN)

Table Title

Enteral vs Parenteral Nutrition — Quick Comparison

Rows

Values

  • Intact protein
  • Complex carbs
  • Long-chain triglycerides (LCT)
  • ~300 mOsm/L
  • Normal GI function; most common; default choice

Property

Polymeric (Standard)

Values

  • Amino acids (elemental) or dipeptides (semi)
  • Simple sugars (elemental)
  • MCT (medium-chain triglycerides)
  • ~550 mOsm/L (higher; hyperosmolar)
  • Impaired digestion/absorption (pancreatitis, Crohn's, short-bowel); reduced lactose

Property

Elemental / Semi-elemental

Values

  • High-quality protein (essential AAs only)
  • Low carb
  • Higher fat
  • Variable
  • Chronic kidney disease (pre-dialysis); ESRD on dialysis

Property

Disease-specific (Renal)

Values

  • BCAA-enriched (branched-chain amino acids)
  • Higher carb
  • Higher fat
  • Variable
  • Hepatic encephalopathy, cirrhosis (reduce aromatic AAs, increase BCAA)

Property

Disease-specific (Hepatic)

Values

  • Standard/higher protein
  • Lower simple sugars, higher complex carbs + fiber
  • Higher fat
  • Variable
  • Type 2 diabetes, glucose intolerance (slower gastric emptying, stable glucose)

Property

Disease-specific (Diabetic)

Columns

  • Formula Type
  • Protein Source
  • Carbohydrate
  • Fat
  • Osmolality
  • When to Use

Table Title

Formula Types — Enteral Nutrition

Rows

Values

  • Vertical removal of ~75% of stomach; reduces ghrelin
  • ~150 mL (no bypass)
  • Moderate (50–60% excess weight loss)
  • MINIMAL (no bowel bypass)
  • Lower (no anatomic bypass)

Property

Sleeve Gastrectomy

Values

  • Small gastric pouch (~30 mL) + jejunum anastomosed to pouch, bypassing stomach & proximal small bowel
  • ~30 mL (very small initially, stretches)
  • Greater (60–75% excess weight loss)
  • SIGNIFICANT (protein, B12, iron, folate, Ca, vitamin D, thiamine bypass absorption sites)
  • HIGHER (rapid gastric emptying into jejunum; dumping in >30% patients)

Property

Roux-en-Y Bypass

Columns

  • Surgery Type
  • Mechanism
  • Pouch Size
  • Weight Loss
  • Malabsorption Risk
  • Dumping Syndrome Risk

Table Title

Bariatric Surgery Types — Restrictions & Malabsorption

Rows

Values

  • <18.5 kg/m²
  • <18.5 kg/m²
  • Malnutrition risk; immune impairment

Property

Underweight

Values

  • 18.5–24.9 kg/m²
  • 18.5–22.9 kg/m²
  • Optimal health; lower cardiovascular risk

Property

Normal weight

Values

  • 25–29.9 kg/m²
  • ≥23 kg/m²
  • EARLY cardiometabolic risk in Asian populations (earlier than WHO cut-off); screening warranted

Property

Overweight

Values

  • 30–34.9 kg/m²
  • ≥27.5 kg/m²
  • Significant health risk; intervention recommended

Property

Obese Class I

Values

  • ≥35 kg/m²
  • Not separately defined (use ≥27.5)
  • Severe obesity; bariatric surgery candidate

Property

Obese Class II / III

Columns

  • Category
  • WHO Standard
  • Asian/Filipino Cut-Off
  • Clinical Significance

Table Title

BMI Classification — Standard vs Asian Cut-Offs

Rows

Values

  • Abrupt TPN cessation; pancreas still secreting insulin against glucose load
  • Sudden weakness, sweating, tachycardia, confusion, seizure (severe)
  • TAPER TPN gradually; hang D10W at same rate if next bag delayed; NEVER use saline

Property

Rebound Hypoglycemia

Values

  • High dextrose concentration; stress response; inadequate insulin
  • Blood glucose >180 mg/dL (often on Day 1–2 of TPN)
  • Sliding-scale insulin; increase infusion time (dilute dextrose); monitor closely

Property

Hyperglycemia

Values

  • Disconnection of tubing during line changes; air enters central vein
  • Sudden dyspnea, chest pain, hypotension, altered mental status (severe)
  • Position LEFT lateral, Trendelenburg, O2; patient VALSALVA during line reconnection (prevention)

Property

Air Embolism

Values

  • Contamination during insertion or dressing changes; TPN is ideal growth medium
  • Fever (usually >38.5°C), chills, positive blood culture, elevated WBC
  • Remove/replace catheter; blood cultures × 2 before antibiotics; broad-spectrum Abx; consider antifungal if prolonged

Property

Catheter-Related Bloodstream Infection (CRBSI)

Values

  • Mechanical irritation, hypercoagulability, long-term TPN catheter
  • Arm/neck swelling, pain, positional occlusion (line won't draw blood)
  • Imaging (ultrasound, CT); heparin/thrombolytics if fresh; catheter replacement if chronic

Property

Thrombosis

Values

  • Long-term TPN (>2–3 weeks), high carbohydrate load, impaired glycemic control
  • Elevated liver enzymes (ALT, AST), hyperbilirubinemia, cholestasis
  • Reduce carbohydrate load; ensure adequate protein; monitor LFTs; lipid emulsion reduction; advance enteral nutrition

Property

Hepatic Dysfunction

Values

  • Aggressive TPN in malnourished patient; carbohydrate triggers insulin surge
  • HYPOphosphatemia, HYPOkalemia, HYPOmagnesemia; weakness, cardiac arrhythmias, respiratory failure
  • START LOW (10–15 kcal/kg) and SLOW; give thiamine before feeding; monitor/replace phosphate, K+, Mg2+ daily × 5 days

Property

Refeeding Syndrome

Columns

  • Complication
  • Cause
  • Signs/Symptoms
  • Management

Table Title

TPN Complications — Recognition & Management

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